Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3795369 | 1.00 | NPSR1 (0.37) | NPSR1LMNAMETAP2PGRMEN1 | |
| SCHEMBL3026279 | 0.91 | LMNA (0.42) | NPSR1LMNAMETAP2PGRMEN1 | |
| SCHEMBL3026281 | 0.91 | LMNA (0.42) | NPSR1LMNAMETAP2PGRMEN1 | |
| SCHEMBL3024546 | 0.88 | HDAC1 (0.35) | NPSR1LMNAMAPTHPGDHDAC1 | |
| SCHEMBL3024543 | 0.88 | HDAC1 (0.35) | NPSR1LMNAMAPTHPGDHDAC1 | |
| SCHEMBL3792520 | 0.86 | LMNA (0.33) | NPSR1LMNAMETAP2PGRKMT2A | |
| SCHEMBL3792522 | 0.86 | LMNA (0.33) | NPSR1LMNAMETAP2PGRKMT2A | |
| SCHEMBL3795401 | 0.86 | NPSR1 (0.35) | NPSR1LMNAMETAP2PGRMEN1 | |
| SCHEMBL3795398 | 0.86 | NPSR1 (0.35) | NPSR1LMNAMETAP2PGRMEN1 | |
| SCHEMBL3795497 | 0.86 | ALDH1A1 (0.34) | NPSR1LMNAMEN1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152047-A1 | Piperazine Compounds Whith a Herbicidal Action | BASF SE (DE) | 2010-06-17 | — | — | US | claimed |
| EP-2054395-A2 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | Basf Se (DE) | 2009-05-06 | — | — | EP | claimed |
| WO-2008152073-A2 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2008-12-18 | — | — | WO | claimed |
| US-20100152047-A1 | Piperazine Compounds Whith a Herbicidal Action | BASF SE (DE) | 2010-06-17 | — | — | US | disclosed |
| EP-2054395-A2 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | Basf Se (DE) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008152073-A2 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152047-A1 | Piperazine Compounds Whith a Herbicidal Action | CBR3, CBR1, CNPY2 | NPSR1 336/4885LMNA 1633/4885METAP2 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.