⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28724578 | 1.00 | — | — | |
| SCHEMBL8934381 | 1.00 | — | — | |
| SCHEMBL19204118 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL5075041 | 0.74 | — | — | |
| SCHEMBL14191652 | 0.74 | — | — | |
| SCHEMBL1223513 | 0.74 | — | — | |
| SCHEMBL360722 | 0.74 | — | — | |
| SCHEMBL17641688 | 0.74 | — | — | |
| SCHEMBL14853052 | 0.74 | — | — | |
| SCHEMBL12952000 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039663-B1 | PROCESS FOR PREPARING CROSSLINKED SATURATED POLYMERS, AND THESE POLYMERS | CIBA-GEIGY AG (CH) | 1985-08-28 | — | — | EP | claimed |
| US-4348511-A | POLYURETHANES MODIFIED WITH BETA-AMINOCROTONIC ACID DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1982-09-07 | — | — | US | claimed |
| EP-0012424-B1 | PROCESS FOR THE PREPARATION OF BETA-ISOBUTYRYLAMINOCROTONAMIDE | Consortium für elektrochemische Industrie GmbH (DE) | 1981-08-05 | — | — | EP | claimed |
| US-4052397-A | PROCESS FOR THE PRODUCTION OF 2-ALKYL OR 2-CYCLOALKYL-4-METHYL-6-HYDROXYPYRIMIDINES | CIBA-GEIGY CORPORATION (US) | 1977-10-04 | — | — | US | claimed |
| JP-8040904-A | — | — | None | — | — | JP | disclosed |
| JP-2169572-A | — | — | None | — | — | JP | disclosed |
| CN-119768401-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-119604530-A | Administration of treatment with anti-FCRH 5/anti-CD 3 bispecific antibodies | 基因泰克公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-119585308-A | Administration of therapy with anti-FCRH 5/anti-CD 3 bispecific antibodies | 基因泰克公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119487067-A | Administration of treatment with anti-FCRH 5/anti-CD 3 bispecific antibodies | 基因泰克公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-117980309-A | Tricyclic fused pyrimidine compounds useful as HER2 inhibitors | 百时美施贵宝公司 | 2024-05-03 | — | — | CN | disclosed |
| US-4291146-A | Heat-curable mixtures, which are stable on storage, of expoxide resins and β-aminocrotonic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1981-09-22 | — | — | US | disclosed |
| US-4217363-A | Preservation of aqueous systems with α-chloro-β-aminocrotonamide | GIVAUDAN CORPORATION (US) | 1980-08-12 | — | — | US | disclosed |
| US-4163848-A | Process for the production of 2-alkyl- or cycloalkyl-4-methyl-6-hydroxypyrimidines | CIBA-GEIGY CORPORATION (US) | 1979-08-07 | — | — | US | disclosed |
| US-4093654-A | Production of pyridoxine intermediates from diketene | HOFFMANN-LA ROCHE INC. (US) | 1978-06-06 | — | — | US | disclosed |
| US-4052396-A | PROCESS FOR THE PRODUCTION OF 2-ALKYL OR 2-CYCLOALKYL-4-METHYL-6-HYDROXYPYRIMIDINES | CIBA-GEIGY CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
| US-4052397-A | PROCESS FOR THE PRODUCTION OF 2-ALKYL OR 2-CYCLOALKYL-4-METHYL-6-HYDROXYPYRIMIDINES | CIBA-GEIGY CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
| US-4052397-A | PROCESS FOR THE PRODUCTION OF 2-ALKYL OR 2-CYCLOALKYL-4-METHYL-6-HYDROXYPYRIMIDINES | CIBA-GEIGY CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |
| US-4018771-A | Process for the production of 2-alkyl or 2-cycloalkyl-4-methyl-6-hydroxypyrimidines | CIBA-GEIGY CORPORATION (US) | 1977-04-19 | — | — | US | disclosed |