Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22910008 | 0.76 | CNR2 (0.47) | ACHEKMT2AMEN1IDO1TDO2 | |
| SCHEMBL11408107 | 0.74 | IDO1 (0.36) | IDO1TDO2 | |
| SCHEMBL6869750 | 0.73 | ACP3 (0.44) | ACHEALDH1A1LMNACYP3A4GAA | |
| SCHEMBL615095 | 0.72 | MAPT (0.46) | ACHEKMT2AMEN1IDO1TDO2 | |
| SCHEMBL28542566 | 0.71 | MAPT (0.39) | KMT2AMEN1IDO1TDO2ALDH1A1 | |
| SCHEMBL28530766 | 0.71 | MAPT (0.39) | KMT2AMEN1IDO1TDO2ALDH1A1 | |
| SCHEMBL28530765 | 0.71 | MAPT (0.39) | KMT2AMEN1IDO1TDO2ALDH1A1 | |
| SCHEMBL30232579 | 0.71 | KMT2A (0.54) | KMT2AMEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL3963434 | 0.71 | KMT2A (0.43) | ACHEKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL617039 | 0.71 | KMT2A (0.54) | KMT2AMEN1ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398765-A1 | IMPROVED PROCESS FOR THE PREPARATION OF (R)-2-(3-DIISOPROPYLAMINO)-1-PHENYLPROPYL)-4METHYLPHENOL AND SALTS THEREOF | Pharmathen S.A. (GR) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010094292-A1 | IMPROVED PROCESS FOR THE PREPARATION OF (R)-2-(3-DIISOPROPYLAMINO)-1-PHENYLPROPYL)-4METHYLPHENOL AND SALTS THEREOF | PHARMATHEN S.A. (GR) | 2010-08-26 | — | — | WO | disclosed |