Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | TDO2 | P48775 | 3/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ACP3 | P15309 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2106150 | 0.87 | TSHR (0.41) | DPP4TSHRF2TRPA1HTR2A | |
| SCHEMBL6869750 | 0.85 | ACP3 (0.44) | TSHRACP3HTR2ACYP2D6 | |
| SCHEMBL6069562 | 0.80 | CHRNB2 (0.41) | DPP4TSHRF2TRPA1ACP3 | |
| SCHEMBL28217399 | 0.75 | ESR1 (0.56) | IDO1TDO2 | |
| SCHEMBL7493934 | 0.75 | IDO1 (0.48) | IDO1TDO2TSHRCYP2D6 | |
| SCHEMBL5324736 | 0.75 | LMNA (0.50) | IDO1TDO2 | |
| SCHEMBL28385338 | 0.72 | DPP4 (0.38) | DPP4TSHRF2TRPA1HTR2A | |
| SCHEMBL11272528 | 0.72 | CYP2C19 (0.42) | TSHR | |
| SCHEMBL11663962 | 0.70 | DPP4 (0.41) | DPP4TSHRF2TRPA1HTR2A | |
| SCHEMBL5174129 | 0.70 | PBRM1 (0.54) | TSHRTRPA1ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284834-A | Diethynyl aromatic hydrocarbons which homopolymerize and char efficiently after cure | HUGHES AIRCRAFT COMPANY (US) | 1981-08-18 | — | — | US | disclosed |