Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408107 | 0.85 | IDO1 (0.36) | ACP3CYP2D6HTR2ATSHR | |
| SCHEMBL29031377 | 0.80 | ACP3 (0.44) | ACP3ESR1OPRM1CYP2D6SLC22A2 | |
| SCHEMBL2106150 | 0.78 | TSHR (0.41) | CYP2D6HTR2AHRH1GAANPSR1 | |
| SCHEMBL3795426 | 0.73 | ACHE (0.42) | CYP2C19CYP3A4CYP2C9GAALMNA | |
| SCHEMBL6069562 | 0.72 | CHRNB2 (0.41) | ACP3CYP3A4TSHRALDH1A1 | |
| SCHEMBL2422170 | 0.72 | ACP3 (0.52) | ACP3ESR1OPRM1CYP2D6SLC22A2 | |
| SCHEMBL5270216 | 0.72 | ACP3 (0.52) | ACP3ESR1OPRM1CYP2D6SLC22A2 | |
| SCHEMBL10836507 | 0.71 | ESR1 (0.45) | ACP3ESR1OPRM1CYP2D6SLC6A2 | |
| SCHEMBL11603883 | 0.70 | ACP3 (0.55) | ACP3ESR1CYP2D6CHRM2ADRA2A | |
| SCHEMBL710709 | 0.70 | ACP3 (0.50) | ACP3ESR1OPRM1CYP2D6SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438309-A1 | QUINUCLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS M2 AND/OR M3 MUSCARINIC RECEPTOR INHIBITORS | UCB, S.A. (BE) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003033495-A1 | QUINUCLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS M2 AND/OR M3 MUSCARINIC RECEPTOR INHIBITORS | UCB, S.A. (BE) | 2003-04-24 | — | — | WO | disclosed |