Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 13/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL581745 | 0.90 | PLG (0.50) | PLGGABRA1GABRG2GABRB3SIGMAR1 | |
| SCHEMBL582166 | 0.89 | PLG (0.49) | PLGGABRA1GABRG2GABRB3SIGMAR1 | |
| SCHEMBL581429 | 0.88 | SIGMAR1 (0.51) | PLGGABRA1GABRG2GABRB3SIGMAR1 | |
| SCHEMBL581069 | 0.85 | PLG (0.54) | PLGGABRA1GABRG2GABRB3SIGMAR1 | |
| SCHEMBL582131 | 0.85 | PLG (0.45) | PLGGABRA1GABRG2GABRB3SIGMAR1 | |
| SCHEMBL3075689 | 0.84 | PLG (0.43) | PLGGABRA1GABRG2GABRB3P2RX7 | |
| SCHEMBL581928 | 0.83 | PLG (0.42) | PLGGABRA1GABRG2GABRB3SIGMAR1 | |
| SCHEMBL3079068 | 0.83 | PLG (0.42) | PLGGABRA1GABRG2GABRB3SIGMAR1 | |
| SCHEMBL587149 | 0.83 | PLG (0.42) | PLGGABRA1GABRG2GABRB3SIGMAR1 | |
| SCHEMBL28812638 | 0.82 | PLG (0.44) | PLGGABRA1GABRG2GABRB3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117323-A1 | METHOD AND APPARATUS FOR PRODUCING HEAT ENERGY AND CARBON DIOXIDE | ASTRAZENECA AB (SE) | 2010-10-14 | — | — | WO | disclosed |