SCHEMBL3795604

SCHEMBL3795604

CCCCCCCC[Si](O)(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
THRB P10828 2/20 0.38
LMNA P02545 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HSD17B10 Q99714 1/20 0.36
EPHX1 P07099 5/20 0.34
HTT P42858 1/20 0.32
DNM1 Q05193 1/20 0.32
MAPT P10636 1/20 0.32
EPHX2 P34913 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27959604 1.00 TSHR (0.38) TSHRTHRBLMNAMEN1KMT2A
SCHEMBL27959339 1.00 TSHR (0.38) TSHRTHRBLMNAMEN1KMT2A
SCHEMBL27959485 1.00 TSHR (0.38) TSHRTHRBLMNAMEN1KMT2A
SCHEMBL27959504 1.00 TSHR (0.38) TSHRTHRBLMNAMEN1KMT2A
SCHEMBL3802824 1.00 TSHR (0.38) TSHRTHRBLMNAMEN1KMT2A
SCHEMBL27959488 0.90 ALDH1A1 (0.30) TSHRLMNAALDH1A1
SCHEMBL28309105 0.89 LMNA (0.36) TSHRTHRBLMNAMEN1KMT2A
SCHEMBL16609255 0.84
SCHEMBL28986964 0.81 TSHR (0.38) TSHRTHRBLMNAMEN1KMT2A
SCHEMBL3798776 0.81 TSHR (0.38) TSHRTHRBLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7737187-B2 Process for producing inorganic oxide organosol NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-06-15 US disclosed
EP-1544257-B1 Process for producing inorganic oxide organosol NISSAN CHEMICAL IND LTD (JP) 2007-08-22 EP disclosed
US-20050154124-A1 Process for producing inorganic oxide organosol NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2005-07-14 US disclosed
EP-1544257-A2 Process for producing inorganic oxide organosol NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 2005-06-22 EP disclosed