SCHEMBL379576

SCHEMBL379576

CC(C)(C)c1cc(C(C)(C)C)c(OC(c2c(C(C)(C)C)cc(C(C)(C)C)cc2C(C)(C)C)C(CO)(CO)CO)c(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RXRA P19793 13/20 0.33
PPARG P37231 12/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
RARG P13631 5/20 0.32
RARA P10276 2/20 0.32
RARB P10826 2/20 0.32
RXRB P28702 2/20 0.32
RXRG P48443 2/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
XBP1 P17861 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1074119 0.96 RXRA (0.31) RXRAPPARGCYP1A2CYP3A4CYP2C9
SCHEMBL25435252 0.92
SCHEMBL76728 0.90 ALDH1A1 (0.31) RXRAPPARGCYP1A2CYP3A4CYP2C9
Pyrophosphoric Acid SCHEMBL3635254 0.89 RXRA (0.31) RXRAPPARGRARGRARARARB
SCHEMBL29061736 0.88 ALDH1A1 (0.33) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL77036 0.88 SMN1; SMN2 (0.39) CYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL674846 0.87 CYP3A4 (0.35) CYP3A4
SCHEMBL1074117 0.87 RXRA (0.31) RXRAPPARGRARGRARARARB
Phosphine SCHEMBL3163238 0.86 SMN1; SMN2 (0.38) CYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL2186175 0.85 RXRA (0.33) RXRAPPARGCYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2070 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240110041-A1 POLYETHYLENE COMPOSITION FOR USE WITH RECYCLED POLYETHYLENE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-04-04 US claimed
US-20240093007-A1 USE OF RECYCLED POLYETHYLENE IN CLOSURES FOR BOTTLES NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2024-03-21 US claimed
CN-114585676-B Polyethylene composition for use with recycled polyethylene SABIC环球技术有限责任公司 2023-09-29 CN claimed
CN-112791675-B Continuous production system and preparation method of biodegradable copolyester and copolyester 中国纺织科学研究院有限公司 2023-06-27 CN claimed
EP-3649190-B1 POLYETHYLENE COMPOSITION SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-03-29 EP claimed
CN-110869429-B Polyethylene composition SABIC环球技术有限责任公司 2023-02-07 CN claimed
CN-115572576-A Adhesive layer material for single-particle-diameter gravel antiskid wearing layer and preparation method thereof 东南大学 2023-01-06 CN claimed
CN-115537958-A Composition, electret master batch, preparation method and application of electret master batch, and method for preparing melt-blown fabric 比亚迪股份有限公司 2022-12-30 CN claimed
EP-2864310-B1 STABILIZER COMPOSITIONS CONTAINING SUBSTITUTED CHROMAN COMPOUNDS AND METHODS OF USE CYTEC TECH CORP (US) 2022-10-26 EP claimed
CN-115073264-B Pretreatment method of methyl pyran solution in leaf alcohol synthesis reaction and application thereof 山东新和成药业有限公司 2022-10-25 CN claimed
US-6664317-B2 Stabilizer system to attenuate the deleterious effects of gamma irradiation consists of a hindered amine, a compound selected from hydroxylamine, nitrone, amine oxide, benzofuranone or mixture; free of phenol antioxidants CIBA SPECIALTY CHEMICALS CORPORATION 2003-12-16 US claimed
US-20030195282-A1 Stabilized gamma irradiated polyolefins KING ROSWELL E (US) 2003-10-16 US claimed
US-6465548-B1 6-HYDROXYCHROMAN DERIVATIVE WITH PHOSPHORUS AND PHENOLIC ANTIOXIDANTS; HEAT, LIGHT AND OXIDATION STABILITY DURING MOLDING YOSHITOMI FINE CHEMICALS, LTD. (JP) 2002-10-15 US claimed
WO-2002074847-A1 FLAME RETARDANT COMPOSITIONS CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) 2002-09-26 WO claimed
US-20020086924-A1 Stabilized gamma irradiated polyolefins CIBA SPECIALTY CHEMICALS CORP. 2002-07-04 US claimed
EP-0628595-A1 Organic phosphite ester compositions containing hindered piperidinyl light stabilizers GENERAL ELECTRIC COMPANY (US) 1994-12-14 EP claimed
EP-0416321-B1 Crystalline polyolefin composition CHISSO CORP (JP) 1994-11-09 EP claimed
US-5342978-A Organic phosphite ester compositions containing hindered piperdinyl light stabilizers GENERAL ELECTRIC COMPANY (US) 1994-08-30 US claimed
US-5063264-A Molding materials CHISSO CORPORATION (JP) 1991-11-05 US claimed
EP-0416321-A1 Crystalline polyolefin composition Chisso Corporation (JP) 1991-03-13 EP claimed