SCHEMBL379598

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL380010	0.81	KDR (0.43)	CLK4HSD17B10MAPTDYRK1ADYRK1B
	SCHEMBL380530	0.80	KDR (0.43)	ALDH1A1CLK4MEN1KMT2AMAPT
	SCHEMBL379479	0.77	PKM (0.43)	ALDH1A1CYP2D6TSHRMAPK1CYP2C19
	SCHEMBL379851	0.75	MAPT (0.38)	ALDH1A1TSHRHSD17B10HPGDMAPT
	SCHEMBL379599	0.74	ALDH1A1 (0.63)	ALDH1A1CYP2D6TSHRMAPK1CYP2C19
	SCHEMBL2368448	0.69	HTT (0.47)	ALDH1A1CYP2D6TSHRMAPK1CYP2C19
	SCHEMBL379896	0.69	CLK4 (0.59)	ALDH1A1CYP2D6TSHRMAPK1CYP2C19
	SCHEMBL379615	0.66	CLK4 (0.53)	ALDH1A1CYP2D6TSHRMAPK1CYP2C19
	SCHEMBL379789	0.66	KDR (0.44)	ALDH1A1TSHRCLK4TP53HSD17B10
	SCHEMBL2369179	0.65	HTT (0.38)	ALDH1A1CLK4MEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.