Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375537 | 0.85 | NR1H2 (0.42) | ALDH1A1TSHRGLANR1H2NR1H3 | |
| SCHEMBL28092851 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TSHRGLATP53LMNA | |
| Hydrochloric Acid SCHEMBL374900 | 0.84 | NR1H2 (0.41) | ALDH1A1TSHRGLANR1H2NR1H3 | |
| SCHEMBL18203139 | 0.80 | NR1H2 (0.43) | ALDH1A1TSHRGLASMN1; SMN2NR1H2 | |
| SCHEMBL4667661 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRGLATP53LMNA | |
| SCHEMBL28292699 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRGLATP53LMNA | |
| SCHEMBL11763140 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRGLATP53LMNA | |
| SCHEMBL9324872 | 0.76 | TSHR (0.48) | ALDH1A1TSHRGLATP53LMNA | |
| SCHEMBL2163020 | 0.75 | GPR88 (0.44) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30401308 | 0.75 | TSHR (0.47) | ALDH1A1TSHRGLATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408450-A1 | A NOVEL ALPHA-(N-SULFONAMIDO)ACETAMIDE COMPOUND AS AN INHIBITOR OF BETA AMYLOID PEPTIDE PRODUCTION | Bristol-Myers Squibb Company (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010107435-A1 | A NOVEL ALPHA-(N-SULFONAMIDO)ACETAMIDE COMPOUND AS AN INHIBITOR OF BETA AMYLOID PEPTIDE PRODUCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-09-23 | — | — | WO | disclosed |