Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMI1 | P35226 | 3/20 | 0.34 |
| ▸ | SCD | O00767 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3793928 | 0.84 | MAPK1 (0.36) | NPC1RAB9AGAAMAPTKDM4E | |
| SCHEMBL3792403 | 0.82 | BMI1 (0.35) | BMI1SCDNPC1RAB9AGAA | |
| SCHEMBL10010389 | 0.80 | FFAR1 (0.41) | — | |
| SCHEMBL1708083 | 0.78 | LMNA (0.43) | SCDALDH1A1 | |
| SCHEMBL3794440 | 0.78 | ALDH1A1 (0.37) | NPC1RAB9AGAAMAPTMEN1 | |
| SCHEMBL1708081 | 0.76 | SCD (0.36) | BMI1SCDNPC1RAB9AGAA | |
| SCHEMBL3795926 | 0.75 | NPC1 (0.37) | BMI1NPC1RAB9AGAAMAPT | |
| SCHEMBL3791787 | 0.74 | MAPT (0.32) | GAAMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL1708275 | 0.74 | BMI1 (0.37) | BMI1ALDH1A1 | |
| SCHEMBL3795912 | 0.73 | PDE10A (0.35) | NPC1RAB9AGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |