Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 4/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 2/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1090210 | 0.89 | — | — | |
| SCHEMBL17766840 | 0.89 | TSHR (0.47) | TSHRTDP1ALDH1A1MAPK1ANPEP | |
| SCHEMBL15658 | 0.89 | — | — | |
| SCHEMBL1089695 | 0.89 | — | — | |
| Ethylene Glycol SCHEMBL28094184 | 0.87 | TDP1 (0.47) | TSHRTDP1ALDH1A1MAPK1ANPEP | |
| Butanol SCHEMBL1682662 | 0.87 | TSHR (0.67) | TSHRTDP1ALDH1A1MAPK1ANPEP | |
| Isobutanol SCHEMBL144682 | 0.87 | TSHR (0.60) | TSHRTDP1ALDH1A1MAPK1ANPEP | |
| Methyl Alcohol SCHEMBL19457756 | 0.86 | — | — | |
| SCHEMBL27750160 | 0.86 | — | — | |
| SCHEMBL27825545 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3371290-B1 | LOW VISCOSITY GEAR LUBRICANTS | LUBRIZOL CORP (US) | 2020-07-08 | — | — | EP | claimed |
| EP-0958278-B1 | PROCESS TO SEPARATE EPSILON-CAPROLACTAM FROM 6-AMINOCAPROAMIDE AND 6-AMINOCAPROAMIDE OLIGOMERS | DSM IP ASSETS BV (NL) | 2004-05-12 | — | — | EP | claimed |
| EP-0927160-B1 | PROCESS FOR THE PREPARATION OF EPSILON-CAPROLACTAM | DSM NV (NL) | 2003-02-12 | — | — | EP | claimed |
| EP-0148145-B1 | PROCESS FOR MAKING NITRODIARYLAMINES | Monsanto Company (US) | 1986-12-30 | — | — | EP | claimed |
| CN-112553035-A | Method for accelerating aging of table vinegar | 江南大学 | 2021-03-26 | — | — | CN | disclosed |
| US-8741554-B2 | Patterning process and resist composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-06-03 | — | — | US | disclosed |
| US-20130012373-A1 | S-TRIAZINE SUNSCREENS BEARING HINDERED PARA-AMINOBENZALMALONATE/PARA-AMINOBENZALMALONAMIDE AND AMINOBENZOATE/AMINOBENZAMIDE SUBSTITUENTS | L'OREAL (FR) | 2013-01-10 | — | — | US | disclosed |
| US-8323624-B2 | S-triazine sunscreens bearing hindered para-aminobenzalmalonate/para-aminobenzalmalonamide and aminobenzoate/aminobenzamide substituents | L'OREAL (FR) | 2012-12-04 | — | — | US | disclosed |
| US-20100304297-A1 | PATTERNING PROCESS AND RESIST COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-02 | — | — | US | disclosed |
| WO-2009074409-A1 | S-TRIAZINE COMPOUNDS CONTAINING ONE AMINOSILOXANE GROUP AND TWO PARTICULAR PARA-AMINOBENZALMALONATE GROUPS; COSMETIC COMPOSITIONS CONTAINING SAID DERIVATIVES; USES OF SAID S-TRIAZINE DERIVATIVES | L'OREAL (FR) | 2009-06-18 | — | — | WO | disclosed |
| US-20080008669-A1 | Photostable sunscreen compositions comprising cinnamate ester UV-B filters and s-triazine compounds | L'OREAL (FR) | 2008-01-10 | — | — | US | disclosed |
| US-20070218022-A1 | Photostable sunscreen compositions comprising cinnamic acid ester UV-B filters, dibenzoylmethane UV-A filters and s-triazine compounds | L'OREAL, PARIS, FRANCE | 2007-09-20 | — | — | US | disclosed |
| US-20070196294-A1 | Photostable sunscreen compositions comprising dibenzoylmethane compound UV-A filters and s-triazine compounds | L'OREAL (FR) | 2007-08-23 | — | — | US | disclosed |
| US-20060045859-A1 | S-triazine sunscreens bearing hindered para-aminobenzalmalonate/para-aminobenzalmalonamide and aminobenzoate/aminobenzamide substituents | L'OREAL (FR) | 2006-03-02 | — | — | US | disclosed |
| US-5410083-A | Synthesis of diaminoresorcinal from resorcinol | THE DOW CHEMICAL COMPANY (US) | 1995-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070218022-A1 | Photostable sunscreen compositions comprising cinnamic acid ester UV-B filters, dibenzoylmethane UV-A filters and s-triazine compounds | NISCH, SUN2, CDC73 | TSHR 3036/4885TDP1 2555/4885ALDH1A1 928/4885 |
| US-20060045859-A1 | S-triazine sunscreens bearing hindered para-aminobenzalmalonate/para-aminobenzalmalonamide and aminobenzoate/aminobenzamide substituents | TYR, ARSA, TST | TSHR 3503/4885TDP1 2165/4885ALDH1A1 623/4885 |
| US-20130012373-A1 | S-TRIAZINE SUNSCREENS BEARING HINDERED PARA-AMINOBENZALMALONATE/PARA-AMINOBENZALMALONAMIDE AND AMINOBENZOATE/AMINOBENZAMIDE SUBSTITUENTS | TYR, ARSA, TST | TSHR 3503/4885TDP1 2165/4885ALDH1A1 623/4885 |
| US-20080008669-A1 | Photostable sunscreen compositions comprising cinnamate ester UV-B filters and s-triazine compounds | NISCH, SUN2, ERCC5 | TSHR 2805/4885TDP1 3264/4885ALDH1A1 1094/4885 |
| US-20070196294-A1 | Photostable sunscreen compositions comprising dibenzoylmethane compound UV-A filters and s-triazine compounds | SUN2, ERCC5, NISCH | TSHR 3342/4885TDP1 1492/4885ALDH1A1 1312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.