SCHEMBL3797108

SCHEMBL3797108

CCCCC(CCC)Cc1c(C)cccc1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
CYP3A4 P08684 3/20 0.42
CA2 P00918 1/20 0.42
KDM4E B2RXH2 3/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
RECQL P46063 1/20 0.40
PTGES O14684 1/20 0.39
ALOX5 P09917 1/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
MYC P01106 1/20 0.39
LMNA P02545 2/20 0.39
CXCR5 P32302 2/20 0.38
TSHR P16473 2/20 0.38
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11422395 0.82 ALDH1A1 (0.52) ALDH1A1CYP3A4CA2KDM4EHSD17B10
SCHEMBL3797295 0.81 PPARA (0.44) ALDH1A1CYP3A4CA2KDM4EKMT2A
SCHEMBL6265203 0.80 ALDH1A1 (0.47) ALDH1A1CA2KMT2AMEN1PPARG
SCHEMBL3799939 0.79 PPARA (0.40) ALDH1A1CYP3A4CA2KDM4EKMT2A
SCHEMBL29757688 0.79 PRSS1 (0.44) ALDH1A1CYP3A4CA2KDM4EHSD17B10
SCHEMBL6859420 0.79 KDM4E (0.52) ALDH1A1CYP3A4KDM4EHPGDHSD17B10
SCHEMBL29672612 0.78 ALDH1A1 (0.48) ALDH1A1CYP3A4CA2KDM4EKMT2A
SCHEMBL9281467 0.78 LMNA (0.53) ALDH1A1CYP3A4CA2KDM4EKMT2A
SCHEMBL7165074 0.78 ALDH1A1 (0.48) ALDH1A1CYP3A4CA2KDM4EKMT2A
SCHEMBL6684614 0.77 ALDH1A1 (0.47) ALDH1A1CYP3A4CA2KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8633244-B2 Cosmetic compositions comprising esters based on 2-propylheptanol COGNIS IP MANAGEMENT GMBH (DE) 2014-01-21 US disclosed
US-8633333-B2 Cosmetic compositions comprising esters based on 2-propylheptanol COGNIS IP MANAGEMENT GMBH (DE) 2014-01-21 US disclosed
US-20130006010-A1 Cosmetic Compositions Comprising Esters Based on 2-Propylheptanol COGNIS IP MANAGEMENT GMBH (DE) 2013-01-03 US disclosed
US-20130004555-A1 Cosmetic Compositions Comprising Esters Based on 2-Propylheptanol COGNIS IP MANAGEMENT GMBH (DE) 2013-01-03 US disclosed
US-8288436-B2 Cosmetic compositions comprising esters based on 2-propylheptanol COGNIS IP MANAGEMENT GMBH (DE) 2012-10-16 US disclosed
US-20100120910-A1 Cosmetic Compositions Comprising Esters Based on 2-Propylheptanol COGNIS IP MANAGEMENT GMBH (DE) 2010-05-13 US disclosed