Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851615 | 0.87 | TDP1 (0.56) | MEN1KMT2ATDP1EPHX1GAA | |
| SCHEMBL15778213 | 0.83 | TDP1 (0.42) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL15796451 | 0.82 | TDP1 (0.44) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL13627401 | 0.81 | EPHX1 (0.62) | MEN1KMT2AALDH1A1TDP1EPHX1 | |
| SCHEMBL2951842 | 0.80 | EPHX1 (0.51) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL2951839 | 0.80 | EPHX1 (0.51) | MEN1KMT2AALDH1A1TSHRTDP1 | |
| SCHEMBL572952 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1TSHREPHX1 | |
| SCHEMBL1498337 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1TSHREPHX1 | |
| SCHEMBL12692961 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1TSHREPHX1 | |
| SCHEMBL24435259 | 0.78 | EPHX1 (0.58) | MEN1KMT2AALDH1A1TDP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408767-B1 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | LUNDBECK & CO AS H (DK) | 2013-07-10 | — | — | EP | disclosed |
| EP-2408767-B1 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | LUNDBECK & CO AS H (DK) | 2013-07-10 | — | — | EP | disclosed |
| US-20120101078-A1 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | H. LUNDBRCK A/S (DK) | 2012-04-26 | — | — | US | disclosed |
| EP-2408767-A2 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | H. Lundbeck A/S (DK) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010108052-A2 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010108052-A2 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101078-A1 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | NPY5R, NPY1R, NPY2R | MEN1 4129/4885KMT2A 1750/4885ALDH1A1 4710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.