Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867268 | 0.87 | KDM4E (0.43) | HPGDALDH1A1KDM4EATMTSHR | |
| SCHEMBL31125987 | 0.84 | ALDH1A1 (0.48) | HPGDALDH1A1KDM4EATMTSHR | |
| SCHEMBL31126023 | 0.82 | ALDH1A1 (0.48) | HPGDALDH1A1KDM4EATMTSHR | |
| SCHEMBL17714990 | 0.79 | TARBP2 (0.48) | HPGDALDH1A1KDM4EATMTSHR | |
| SCHEMBL17113228 | 0.79 | NPC1 (0.48) | HPGDALDH1A1KDM4EATMTSHR | |
| SCHEMBL17241178 | 0.78 | MAPT (0.48) | HPGDALDH1A1KDM4EATMGAA | |
| SCHEMBL8470586 | 0.76 | AOC3 (0.44) | HPGDALDH1A1KDM4EATMTSHR | |
| SCHEMBL28267216 | 0.75 | MAPK1 (0.34) | HPGDALDH1A1KDM4EATMTSHR | |
| SCHEMBL13091722 | 0.73 | KDM4E (0.44) | HPGDALDH1A1KDM4EATMTSHR | |
| SCHEMBL13160311 | 0.73 | ALDH1A1 (0.36) | HPGDALDH1A1GAAPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117425-A1 | CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | BIOGEN IDEC MA INC. (US) | 2010-10-14 | — | — | WO | disclosed |