Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 20/20 | 0.46 |
| ▸ | OXTR | P30559 | 4/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.43 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3803453 | 0.92 | AVPR1B (0.41) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL3798738 | 0.92 | AVPR1B (0.55) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL3797263 | 0.91 | AVPR1B (0.46) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL3714952 | 0.89 | AVPR1B (0.37) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL3716573 | 0.89 | AVPR1B (0.37) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL3715725 | 0.88 | AVPR1B (0.37) | AVPR1BOXTRAVPR1AAVPR2 | |
| SCHEMBL12761108 | 0.87 | AVPR1B (0.44) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL1590658 | 0.85 | AVPR1B (0.46) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL1591735 | 0.84 | AVPR1B (0.54) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL1591303 | 0.84 | AVPR1B (0.46) | AVPR1BOXTRAVPR1AAVPR2GPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231645-A2 | 5-HALOGEN-SUBSTITUTED OXINDOLE DERIVATIVES AND USE THEREOF FOR TREATING VASOPRESSINE-DEPENDENT DISEASES | Abbott GmbH & Co. KG (DE) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009071689-A2 | 5-HALOGEN-SUBSTITUTED OXINDOLE DERIVATIVES AND USE THEREOF FOR TREATING VASOPRESSINE-DEPENDENT DISEASES | ABBOTT GMBH & CO. KG (DE) | 2009-06-11 | — | — | WO | disclosed |