Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | SQLE | Q14534 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379518 | 0.86 | MAPT (0.42) | MAPTSMYD3ALDH1A1TSHRMEN1 | |
| SCHEMBL5009722 | 0.84 | MAPT (0.45) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL379473 | 0.83 | MAPT (0.44) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL4222468 | 0.80 | MAPT (0.47) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL19893800 | 0.80 | MAPT (0.47) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL19909758 | 0.80 | MAPT (0.47) | MAPTALDH1A1TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL19893791 | 0.79 | MAPT (0.46) | MAPTALDH1A1TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL19893793 | 0.79 | MAPT (0.46) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5070265 | 0.79 | MAPT (0.50) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL31741885 | 0.77 | ALDH1A1 (0.45) | CYP1A2SMYD3ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408767-A2 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | H. Lundbeck A/S (DK) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010108052-A2 | AMIDE DERIVATIVES AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | H. LUNDBECK A/S (DK) | 2010-09-23 | — | — | WO | disclosed |