Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4222468 | 1.00 | MAPT (0.47) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL19893800 | 1.00 | MAPT (0.47) | MAPTALDH1A1TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL19893793 | 0.98 | MAPT (0.46) | MAPTALDH1A1TSHRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL19893791 | 0.98 | MAPT (0.46) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL5009722 | 0.86 | MAPT (0.45) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1722155 | 0.85 | GAA (0.44) | ALDH1A1GAAPPM1BPTPN1PPP1CC | |
| SCHEMBL1722156 | 0.85 | GAA (0.44) | ALDH1A1GAAPPM1BPTPN1PPP1CC | |
| SCHEMBL1701062 | 0.85 | MAPT (0.50) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL379473 | 0.84 | MAPT (0.44) | MAPTALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL8891623 | 0.84 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2APPM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10189804-B2 | Method for producing dicarboxylic acid compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-01-29 | — | — | US | disclosed |
| US-20180148424-A1 | METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-05-31 | — | — | US | disclosed |
| US-20180148424-A1 | METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-05-31 | — | — | US | disclosed |
| EP-3287448-A1 | METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189804-B2 | Method for producing dicarboxylic acid compound | PC, CPS1, PCCA | MAPT 3033/4885ALDH1A1 294/4885TSHR 3294/4885 |
| US-20180148424-A1 | METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND | PC, CPS1, PCCA | MAPT 3033/4885ALDH1A1 294/4885TSHR 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.