SCHEMBL3797332

SCHEMBL3797332

CC1(C)COB(c2ccc(C#Cc3cncnc3)cc2)OC1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 10/20 0.47
SNCA P37840 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3713341 0.86 GRM5 (0.44) GRM5
SCHEMBL3788618 0.85 SNCA (0.38) GRM5SNCA
SCHEMBL3788621 0.81 APP (0.40) GRM5SNCA
SCHEMBL13187979 0.80 SNCA (0.43) SNCA
SCHEMBL3786338 0.80 GRM5 (0.37) GRM5SNCA
SCHEMBL20312473 0.79 SNCA (0.35) SNCA
SCHEMBL4264297 0.77 SNCA (0.44) SNCA
SCHEMBL3709305 0.77 SNCA (0.34) SNCA
SCHEMBL3797602 0.75 ACACB (0.38) SNCA
SCHEMBL3721364 0.75 FFAR1 (0.40) GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010100475-A1 HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS ASTRAZENECA AB (SE) 2010-09-10 WO disclosed