Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 16/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188128 | 0.84 | SNCA (0.40) | SNCA | |
| SCHEMBL3709305 | 0.82 | SNCA (0.34) | SNCA | |
| SCHEMBL3797332 | 0.80 | GRM5 (0.47) | GRM5SNCA | |
| SCHEMBL3713341 | 0.77 | GRM5 (0.44) | GRM5CYP1A2 | |
| SCHEMBL3788618 | 0.76 | SNCA (0.38) | GRM5SNCA | |
| SCHEMBL3788621 | 0.76 | APP (0.40) | GRM5SNCA | |
| SCHEMBL3797602 | 0.73 | ACACB (0.38) | SNCA | |
| SCHEMBL3721364 | 0.73 | FFAR1 (0.40) | GRM5CYP1A2 | |
| SCHEMBL2441571 | 0.73 | SNCA (0.38) | SNCA | |
| SCHEMBL3785499 | 0.72 | TNF (0.40) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |