Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.51 |
| ▸ | CNR1 | P21554 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084849 | 1.00 | CNR2 (0.51) | CNR2CNR1MEN1KMT2AATM | |
| SCHEMBL3813611 | 0.87 | MAPK8 (0.56) | CNR2CNR1MEN1KMT2AATM | |
| SCHEMBL4085846 | 0.87 | MAPK8 (0.56) | CNR2CNR1MEN1KMT2AATM | |
| SCHEMBL4080526 | 0.86 | MAPK8 (0.52) | CNR2CNR1MEN1KMT2AATM | |
| SCHEMBL3743041 | 0.85 | CNR2 (0.46) | CNR2CNR1MAPT | |
| SCHEMBL3756414 | 0.85 | CNR2 (0.64) | CNR2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4095706 | 0.83 | TP53 (0.64) | CNR2TP53POLBALDH1A1GAA | |
| SCHEMBL3808536 | 0.83 | CNR2 (0.66) | CNR2CNR1MEN1KMT2ATP53 | |
| SCHEMBL4084439 | 0.83 | CNR2 (0.66) | CNR2CNR1MEN1KMT2ATP53 | |
| SCHEMBL4084850 | 0.82 | L3MBTL1 (0.56) | CNR2MEN1KMT2ATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176219-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009009550-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-01-15 | — | — | WO | disclosed |