Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | EEF2K | O00418 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2053963 | 0.97 | LMNA (0.36) | ALDH1A1LMNAOPRL1L3MBTL1TSHR | |
| SCHEMBL2016931 | 0.95 | LMNA (0.38) | ALDH1A1LMNAOPRL1L3MBTL1TSHR | |
| SCHEMBL2040851 | 0.93 | LMNA (0.39) | ALDH1A1LMNAOPRL1L3MBTL1TSHR | |
| SCHEMBL2037379 | 0.87 | PDE4A (0.34) | ALDH1A1LMNAOPRL1L3MBTL1TSHR | |
| SCHEMBL28088924 | 0.81 | CNR2 (0.38) | ALDH1A1LMNAOPRL1L3MBTL1TSHR | |
| SCHEMBL2035833 | 0.79 | AKR1C1 (0.42) | ALDH1A1LMNAOPRL1L3MBTL1TSHR | |
| SCHEMBL2037649 | 0.79 | AKR1C1 (0.42) | ALDH1A1LMNAOPRL1L3MBTL1TSHR | |
| SCHEMBL30627157 | 0.79 | CYP3A4 (0.38) | ALDH1A1LMNAL3MBTL1TSHRMEN1 | |
| SCHEMBL2035761 | 0.77 | OPRL1 (0.40) | ALDH1A1LMNAOPRL1L3MBTL1TSHR | |
| SCHEMBL30627103 | 0.74 | CYP3A4 (0.37) | ALDH1A1LMNAL3MBTL1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118208-A1 | BENZOXAZEPIN-4- (5H) -YL DERIVATIVES AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |