Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040851 | 0.84 | LMNA (0.39) | ALDH1A1TSHRNOS1HSD17B10OPRL1 | |
| SCHEMBL3797646 | 0.81 | ALDH1A1 (0.35) | ALDH1A1TSHRNOS1HSD17B10OPRL1 | |
| SCHEMBL2053963 | 0.81 | LMNA (0.36) | ALDH1A1TSHRNOS1HSD17B10OPRL1 | |
| SCHEMBL2016931 | 0.80 | LMNA (0.38) | ALDH1A1TSHRNOS1HSD17B10OPRL1 | |
| SCHEMBL2037379 | 0.79 | PDE4A (0.34) | ALDH1A1TSHRNOS1HSD17B10OPRL1 | |
| SCHEMBL2640915 | 0.73 | ALDH1A1 (0.38) | CNR2ALDH1A1BACE1TSHRNOS1 | |
| SCHEMBL2053631 | 0.73 | OPRL1 (0.44) | CNR2ALDH1A1BACE1TSHRNOS1 | |
| Hydrochloric Acid SCHEMBL14152305 | 0.72 | ALDH1A1 (0.37) | CNR2ALDH1A1BACE1TSHRNOS1 | |
| SCHEMBL2035761 | 0.72 | OPRL1 (0.40) | ALDH1A1TSHROPRL1LMNAL3MBTL1 | |
| SCHEMBL12133618 | 0.69 | CNR2 (0.39) | CNR2ALDH1A1BACE1TSHRNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | claimed |
| CN-103608332-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2016-09-28 | — | — | CN | claimed |