Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GSDMD | P57764 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11648463 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HSD17B10LMNACA12CA1 | |
| SCHEMBL2223153 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HSD17B10LMNACA12CA1 | |
| SCHEMBL7940329 | 0.73 | SOAT1 (0.48) | ALDH1A1HSD17B10LMNACA12CA1 | |
| SCHEMBL18813684 | 0.72 | ALDH1A1 (0.34) | ALDH1A1HSD17B10LMNACA12CA1 | |
| SCHEMBL8755671 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HSD17B10LMNACA12CA1 | |
| SCHEMBL9679886 | 0.70 | — | — | |
| SCHEMBL11692562 | 0.70 | ALDH1A1 (0.48) | ALDH1A1HSD17B10LMNACA12CA1 | |
| SCHEMBL4553199 | 0.70 | — | — | |
| SCHEMBL11001004 | 0.69 | — | — | |
| SCHEMBL10881445 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828341-B1 | AMPHIPHILIC BLOCK COPOLYMERS AND THEIR USE | AMO GRONINGEN BV (NL) | 2010-10-06 | — | — | EP | disclosed |