Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11648463 | 0.86 | ALDH1A1 (0.53) | SOAT1ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL2223153 | 0.79 | ALDH1A1 (0.46) | SOAT1ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL8755671 | 0.77 | ALDH1A1 (0.43) | SOAT1ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL28388179 | 0.77 | ALOX15 (0.46) | SOAT1ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL9679886 | 0.76 | — | — | |
| SCHEMBL3797694 | 0.73 | ALDH1A1 (0.40) | SOAT1ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL20921393 | 0.72 | ALDH1A1 (0.55) | ALDH1A1LMNAHSD17B10GAAKMT2A | |
| SCHEMBL20870669 | 0.72 | ALDH1A1 (0.50) | SOAT1ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL145522 | 0.72 | — | — | |
| SCHEMBL6009969 | 0.72 | ALDH1A1 (0.50) | SOAT1ALDH1A1LMNAHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262114-B1 | NOVEL AMIDINOPHENOL DERIVATIVES; INHIBITORS OF PHOSPHOLIPASE A2 AND/OR TRYPSIN | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-07-17 | — | — | US | claimed |