SCHEMBL3797706

SCHEMBL3797706

CCOC(=O)c1nn(C)c(CC)c1C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
ELANE P08246 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP1A2 P05177 2/20 0.39
PDE4A P27815 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
USP2 O75604 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19615264 0.85 ALDH1A1 (0.40) ADORA3ADORA2AADORA1NPC1RAB9A
SCHEMBL22900489 0.84 KMT2A (0.46) ADORA3ADORA2AADORA1KMT2ANPC1
SCHEMBL26926692 0.82 ADORA3 (0.37) ADORA3ADORA2AADORA1KMT2ANPC1
SCHEMBL12683029 0.82 CYP1A2 (0.46) ADORA3ADORA2AADORA1KMT2ANPC1
SCHEMBL4700865 0.81 ADORA3 (0.47) ADORA3ADORA2AADORA1KMT2ANPC1
SCHEMBL31467465 0.79 HCAR2 (0.43) NPC1ALDH1A1KDM4EUSP2MAPK1
SCHEMBL15568782 0.78 KDM4E (0.43) ADORA3ADORA2AADORA1KMT2ANPC1
SCHEMBL31467462 0.77 ALDH1A1 (0.41) ADORA3ADORA2AADORA1KMT2ANPC1
SCHEMBL17288518 0.77 NPC1 (0.41) ADORA3ADORA2AADORA1KMT2ANPC1
SCHEMBL22889786 0.77 KDM4E (0.49) ADORA3ADORA2AADORA1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025049827-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING PYRAZOLE DERIVATIVES OSMO LABS, PBC (US) 2025-03-06 WO disclosed
WO-2010117425-A1 CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE BIOGEN IDEC MA INC. (US) 2010-10-14 WO disclosed