SCHEMBL1243693

SCHEMBL1243693

Nc1ccnc(C(=O)O)c1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.50
ASPH Q12797 5/20 0.50
KDM8 Q8N371 5/20 0.50
MAPT P10636 5/20 0.44
ALDH1A1 P00352 5/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
BLM P54132 1/20 0.44
AGER Q15109 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HTT P42858 1/20 0.44
HSD17B10 Q99714 1/20 0.44
GABRP O00591 3/20 0.42
GABRD O14764 3/20 0.42
GABRA1 P14867 3/20 0.42
GABRB1 P18505 3/20 0.42
GABRG2 P18507 3/20 0.42
GABRB3 P28472 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29860445 1.00 KDM4E (0.50) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL20520334 0.86 KDM4E (0.42) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL22688908 0.81 NAPRT (0.48) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL22688920 0.81 KDM4E (0.47) KDM4EASPHKDM8MAPTALDH1A1
Hydrochloric Acid SCHEMBL20239059 0.80 KDM4E (0.61) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL3798200 0.79 KDM4E (0.46) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL29525861 0.78 KDM4E (0.53) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL7080699 0.78 GRM6 (0.41) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL24813521 0.78 HTT (0.42) KDM4EASPHKDM8MAPTALDH1A1
SCHEMBL2349928 0.78 KDM4E (0.44) KDM4EASPHKDM8MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590343-B2 Corrosion inhibitor composition for magnesium or magnesium alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2020-03-17 US claimed
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP claimed
EP-3284847-A1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2018-02-21 EP claimed
US-20180044590-A1 Corrosion Inhibitor Composition for Magnesium or Magnesium Alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2018-02-15 US claimed
US-20040006103-A1 Use of chloroquine, hydroxychloroquine and 4 amino-quinolinic derivatives to obtain a drug for the anti retroviral therapy, active towards HIV sensitive strains and towards HIV strains which are resistant to both nucleosidic and non-nucleosidic reverse transcriptase inhibitors and to proteases inhibitors VALPHARMA S.A. (SM) 2004-01-08 US claimed
EP-1374867-A1 Use of chloroquine, hydroxychloroquine and 4 amino-quinolinic derivatives to obtain a drug for the anti retroviral therapy, active towards hiv sensitive strains and towards hiv strains which are resistant to both nucleosidic and non-nucleosidic reverse transcriptase inhibitors and to proteases inhibitors Valpharma S.A. (SM) 2004-01-02 EP claimed
EP-0663399-B1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AG (DE) 1998-06-10 EP claimed
US-12515207-B2 Metal-metal bonded ammonia oxidation catalysts WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2026-01-06 US disclosed
US-20250276300-A1 REDUCTION OF MONOMERIC ISOCYANATES BY POROUS MATERIAL BASF SE (DE) 2025-09-04 US disclosed
EP-4291588-B1 REDUCTION OF MONOMERIC ISOCYANATES BY POROUS MATERIAL BASF SE (DE) 2025-08-20 EP disclosed
CN-115368342-B Fibroblast active protein inhibitor, radionuclide marker, preparation method and application thereof 西南医科大学附属医院 2024-01-23 CN disclosed
EP-4291588-A1 REDUCTION OF MONOMERIC ISOCYANATES BY POROUS MATERIAL BASF SE (DE) 2023-12-20 EP disclosed
CN-116829611-A Reduction of monomeric isocyanates by porous materials 巴斯夫欧洲公司 2023-09-29 CN disclosed
US-4921530-A Certain 3,5-pyridine dicarboxylates, their thio analogues having herbicidal activity MONSANTO COMPANY (US) 1990-05-01 US disclosed
US-4835279-A 2,6-substituted pyridine compounds MONSANTO COMPANY (US) 1989-05-30 US disclosed
US-4824954-A FROM ACETONE DIESTER 4-1AMINO-2,3-BIS/HALOALKYL-3,5-PYRIDINEDICARBOXYLATE MONSANTO COMPANY (US) 1989-04-25 US disclosed
US-4797149-A HERBICIDES MONSANTO COMPANY (US) 1989-01-10 US disclosed
US-4698093-A POST, PRE EMERGENTS MONSANTO COMPANY (US) 1987-10-06 US disclosed
EP-0182769-A1 2,6-Substituted pyridine compounds Monsanto Company (US) 1986-05-28 EP disclosed
EP-0181312-A2 Process for preparation of substituted pyridines Monsanto Company (US) 1986-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006103-A1 Use of chloroquine, hydroxychloroquine and 4 amino-quinolinic derivatives to obtain a drug for the anti retroviral therapy, active towards HIV sensitive strains and towards HIV strains which are resistant to both nucleosidic and non-nucleosidic reverse transcriptase inhibitors and to proteases inhibitors QTRT1, NQO2, CTSL KDM4E 600/4885ASPH 402/4885KDM8 365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.