Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL7707813 | 0.92 | TDP1 (0.83) | — | |
| Propylene Glycol SCHEMBL7415535 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL27919821 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL29873191 | 0.91 | — | — | |
| Propylene Glycol SCHEMBL161401 | 0.91 | TDP1 (1.00) | — | |
| Propylene Glycol SCHEMBL15864609 | 0.91 | TDP1 (1.00) | — | |
| Propylene Glycol SCHEMBL724028 | 0.91 | TDP1 (1.00) | — | |
| Propylene Glycol SCHEMBL7522896 | 0.91 | TDP1 (1.00) | — | |
| Propylene Glycol SCHEMBL3535 | 0.91 | — | — | |
| Propylene Glycol SCHEMBL55583 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100196428-A1 | METHOD FOR PRODUCING COSMETIC PREPARATIONS | BASF SE (DE) | 2010-08-05 | — | — | US | disclosed |
| EP-2019085-A1 | Method for producing zinc oxide dispersions for use in cosmetic compositions | BASF SE (DE) | 2009-01-28 | — | — | EP | disclosed |
| WO-2001060328-A9 | DEODORANT WITH SMALL PARTICLE ZINC OXIDE | COLGATE PALMOLIVE CO (US) | 2003-01-16 | — | — | WO | disclosed |
| EP-1255527-A1 | DEODORANT WITH SMALL PARTICLE ZINC OXIDE | Colgate-Palmolive Company (US) | 2002-11-13 | — | — | EP | disclosed |
| US-6358499-B2 | POLYETHERSILOXANE COPOLYMER | COLGATE-PALMOLIVE COMPANY | 2002-03-19 | — | — | US | disclosed |
| US-20010031248-A1 | Deodorant with small particle zinc oxide | COLGATE-PALMOLIVE COMPANY | 2001-10-18 | — | — | US | disclosed |
| WO-2001060328-A1 | DEODORANT WITH SMALL PARTICLE ZINC OXIDE | COLGATE-PALMOLIVE COMPANY (US) | 2001-08-23 | — | — | WO | disclosed |