Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380011 | 0.82 | UTS2R (0.53) | UTS2RPKMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL379904 | 0.81 | UTS2R (0.49) | UTS2REGFRSMN1; SMN2RAB9ATSHR | |
| SCHEMBL379685 | 0.80 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2RAB9ATSHR | |
| SCHEMBL380531 | 0.79 | UTS2R (0.47) | UTS2RPKMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL379503 | 0.78 | TNF (0.50) | PKMEGFRSMN1; SMN2RAB9ATSHR | |
| SCHEMBL379470 | 0.75 | IGF1R (0.42) | MEN1KMT2ASMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL379599 | 0.74 | ALDH1A1 (0.63) | UTS2REGFRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL379480 | 0.74 | CYP1A2 (0.63) | UTS2RPKMEGFRMEN1KMT2A | |
| SCHEMBL379638 | 0.72 | TUBB4A (0.44) | EGFRMEN1KMT2ACLK4DYRK1A | |
| SCHEMBL9375292 | 0.70 | UTS2R (0.61) | UTS2RPKMEGFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968982-B1 | THIENO (3,2-C) PYRIDINE COMPOUNDS | XENTION LTD (GB) | 2012-01-25 | — | — | EP | disclosed |