Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 17/20 | 0.37 |
| ▸ | CDK2 | P24941 | 17/20 | 0.37 |
| ▸ | GSK3B | P49841 | 12/20 | 0.37 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825318 | 0.81 | CYP1A2 (0.45) | CCNE1CDK2GSK3B | |
| SCHEMBL2822798 | 0.78 | CYP4F2 (0.41) | CCNE1CDK2GSK3B | |
| SCHEMBL1650609 | 0.76 | — | — | |
| SCHEMBL2360121 | 0.75 | — | — | |
| SCHEMBL11102141 | 0.75 | — | — | |
| SCHEMBL13621200 | 0.72 | ACE2 (0.44) | CCNE1CDK2GSK3B | |
| SCHEMBL7603557 | 0.72 | MEN1 (0.33) | CCNE1CDK2GSK3B | |
| SCHEMBL22311397 | 0.72 | CCNE1 (0.48) | CCNE1CDK2GSK3B | |
| SCHEMBL752460 | 0.71 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL44691 | 0.70 | HDAC4 (0.35) | HDAC4VHL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393809-A2 | DERIVATIVES OF AZASPIRANYL-ALKYLCARBAMATES OF 5-MEMBER HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089510-A2 | DERIVATIVES OF AZASPIRANYL-ALKYLCARBAMATES OF 5-MEMBER HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-08-12 | — | — | WO | disclosed |