Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3854556 | 0.79 | — | — | |
| SCHEMBL14745845 | 0.76 | TDP1 (0.33) | TDP1 | |
| SCHEMBL44361 | 0.75 | — | — | |
| SCHEMBL3798748 | 0.70 | HDAC4 (0.41) | HDAC4VHL | |
| SCHEMBL14310605 | 0.69 | VHL (0.69) | VHL | |
| SCHEMBL17918751 | 0.69 | CCNE1 (0.38) | VHL | |
| SCHEMBL17916146 | 0.66 | CCNE2 (0.44) | HDAC4NR4A2 | |
| SCHEMBL11833092 | 0.65 | GAA (0.35) | HDAC4NR4A2LMNA | |
| SCHEMBL13411549 | 0.64 | ALDH1A1 (0.49) | TDP1 | |
| SCHEMBL27368805 | 0.64 | NR4A2 (0.35) | HDAC4NR4A2TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | claimed |
| WO-2011137587-A1 | CYTOKINE INHIBITORS | HUTCHISON MEDIPHARMA LIMITED (CN) | 2011-11-10 | — | — | WO | disclosed |