SCHEMBL3799045

SCHEMBL3799045

CCCOCCO[PH](=O)OCCOCCC

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11271176 0.85 TSHR (0.50) CYP3A4TSHRMEN1THRBHTT
SCHEMBL19528677 0.85 TSHR (0.50) CYP3A4TSHRMEN1THRBHTT
SCHEMBL178840 0.84 ALDH1A1 (0.31) TSHR
SCHEMBL20034383 0.84 ALDH1A1 (0.41) TSHRTHRB
SCHEMBL282709 0.83 CA1 (0.33)
SCHEMBL28538157 0.80 CA1 (0.32)
SCHEMBL28538840 0.80 CA1 (0.32)
SCHEMBL28541932 0.80 CA1 (0.32)
SCHEMBL20606618 0.80 CYP3A4 (0.31) CYP3A4TSHRHSD17B10
SCHEMBL14760643 0.79 CA2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9284419-B2 Method of preparing a nanoparticle dispersion of a modified metal oxide CABOT CORPORATION (US) 2016-03-15 US disclosed
EP-2185633-B1 METHOD OF PREPARING A NANOPARTICLE DISPERSION OF A MODIFIED METAL OXIDE CABOT CORP (US) 2014-03-12 EP disclosed
EP-2530108-A1 Method of preparing a polymer composition Cabot Corporation (US) 2012-12-05 EP disclosed
US-20100216911-A1 Method of Preparing a Nanoparticle Dispersion of a Modified Metal Oxide CABOT CORPORATION (US) 2010-08-26 US disclosed
EP-2185633-A2 METHOD OF PREPARING A NANOPARTICLE DISPERSION OF A MODIFIED METAL OXIDE Cabot Corporation (US) 2010-05-19 EP disclosed
WO-2009032072-A2 METHOD OF PREPARING A NANOPARTICLE DISPERSION OF A MODIFIED METAL OXIDE CABOT CORPORATION (US) 2009-03-12 WO disclosed