Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.65 |
| ▸ | AR | P10275 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MITF | O75030 | 2/20 | 0.56 |
| ▸ | CCR6 | P51684 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29937743 | 1.00 | CTSB (0.65) | CTSBARHTTKMT2AALDH1A1 | |
| SCHEMBL3292356 | 0.98 | GAA (0.63) | CTSBARHTTKMT2AALDH1A1 | |
| SCHEMBL29738367 | 0.98 | GAA (0.63) | CTSBARHTTKMT2AALDH1A1 | |
| SCHEMBL7118705 | 0.96 | HTT (0.64) | CTSBARHTTKMT2AALDH1A1 | |
| SCHEMBL1274938 | 0.92 | HTT (0.73) | CTSBARHTTKMT2AALDH1A1 | |
| Acetamide SCHEMBL28113497 | 0.87 | ALDH1A1 (0.60) | CTSBARHTTKMT2AALDH1A1 | |
| SCHEMBL3435076 | 0.85 | CTSB (0.65) | CTSBARHTTKMT2AALDH1A1 | |
| SCHEMBL12932461 | 0.85 | HTT (0.61) | HTTKMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL3055471 | 0.85 | MAPT (0.60) | CTSBARHTTKMT2AALDH1A1 | |
| SCHEMBL14206650 | 0.84 | HTT (0.52) | CTSBARHTTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021209490-A1 | CYCLAMINEPHENYLAMINOQUINOLINES AS FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-10-21 | — | — | WO | disclosed |
| CN-111606926-B | Preparation method of benzimidazole [1,3] azathiazepine compound | 大连理工大学 | 2021-10-15 | — | — | CN | disclosed |
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |
| CN-111606926-A | Preparation method of benzimidazole [1,3] azathia compounds | 大连理工大学 | 2020-09-01 | — | — | CN | disclosed |
| CN-104871036-B | Method for making improved UV-absorbing ophthalmic lenses | 诺华股份有限公司 | 2019-12-10 | — | — | CN | disclosed |
| EP-3542193-A1 | METHOD FOR MAKING OPHTHALMIC LENSES | Novartis AG (CH) | 2019-09-25 | — | — | EP | disclosed |
| US-10338408-B2 | Method for making improved UV-absorbing ophthalmic lenses | NOVARTIS AG (CH) | 2019-07-02 | — | — | US | disclosed |
| US-20180141293-A1 | METHOD FOR MAKING OPHTHALMIC LENSES | ALCON INC. (CH) | 2018-05-24 | — | — | US | disclosed |
| CN-105037386-B | Tetrahydrobenzo [ c ] [1,2,5] oxadiazine compound and preparation method thereof | 大连理工大学 | 2017-10-24 | — | — | CN | disclosed |
| EP-2932314-B1 | METHOD FOR MAKING IMPROVED UV-ABSORBING OPHTHALMIC LENSES | NOVARTIS AG (CH) | 2017-02-01 | — | — | EP | disclosed |
| WO-2006136402-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DEVELOGEN AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | disclosed |
| US-6884801-B1 | Imidazoline derivatives as alpha-1A adrenoceptor ligands | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-26 | — | — | US | disclosed |
| EP-1462453-A1 | Paraphenylenediamin derivatives comprising a substituted pyrrolidinyl group and bearing a cationic radical as well as their use for dyeing keratinic fibres | L'OREAL (FR) | 2004-09-29 | — | — | EP | disclosed |
| EP-1175406-A1 | IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066563-A1 | IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2000-11-09 | — | — | WO | disclosed |
| EP-0444944-B1 | Synthesis and elucidation of azamitosene and iminoazamitosene | RES CORP TECHNOLOGIES INC (US) | 1997-09-24 | — | — | EP | disclosed |
| US-5246955-A | Pyrrolo(1,2-a)benzimidazole 5,8-diones, antitumor | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-09-21 | — | — | US | disclosed |
| EP-0449649-A2 | Antineoplastic quinones and methods of using same | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-10-02 | — | — | EP | disclosed |
| EP-0444944-A2 | Synthesis and elucidation of azamitosene and iminoazamitosene | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-09-04 | — | — | EP | disclosed |
| US-5015742-A | Antitumor agents | ARIZONA BOARD OF REGENTS (US) | 1991-05-14 | — | — | US | disclosed |