Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3790735 | 0.89 | EPHX2 (0.54) | EPHX2KDM4EMAPTGAASMN1; SMN2 | |
| SCHEMBL3788548 | 0.84 | KDM4E (0.50) | EPHX2KDM4EMAPTTSHRMAPK1 | |
| SCHEMBL3794376 | 0.82 | EPHX2 (0.51) | EPHX2TSHRMAPK1RAB9A | |
| SCHEMBL3808293 | 0.80 | EPHX2 (0.47) | EPHX2TSHRMAPK1RAB9A | |
| SCHEMBL26240414 | 0.78 | KDM4E (0.56) | KDM4EMAPTKMT2ATSHR | |
| SCHEMBL6154919 | 0.77 | CYP2C19 (0.48) | EPHX2KDM4EGAAKMT2AMAPK1 | |
| SCHEMBL3796561 | 0.76 | EPHX2 (0.58) | EPHX2MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL3789018 | 0.75 | EPHX2 (0.57) | EPHX2MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL14503273 | 0.75 | SMN1; SMN2 (0.66) | KDM4EMAPTGAASMN1; SMN2KMT2A | |
| SCHEMBL6566257 | 0.75 | EPHX2 (0.71) | EPHX2KDM4EMAPTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112946-A1 | ADAMANTANE BISUREA DERIVATIVES, METHOD OF PREPARATION AND APPLICATION IN ANION SENSING | RUDJER BOSKOVIC INSTITUTE (HR) | 2010-10-07 | — | — | WO | disclosed |