Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 17/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794376 | 0.85 | EPHX2 (0.51) | EPHX2MAPK1TSHRRAB9ADPP8 | |
| SCHEMBL3799290 | 0.80 | EPHX2 (0.58) | EPHX2MAPK1TSHRRAB9A | |
| SCHEMBL3796561 | 0.75 | EPHX2 (0.58) | EPHX2RAB9A | |
| SCHEMBL3789018 | 0.74 | EPHX2 (0.57) | EPHX2RAB9A | |
| SCHEMBL3790735 | 0.72 | EPHX2 (0.54) | EPHX2 | |
| SCHEMBL3788548 | 0.72 | KDM4E (0.50) | EPHX2MAPK1TSHRRAB9A | |
| SCHEMBL26240414 | 0.72 | KDM4E (0.56) | TSHR | |
| SCHEMBL3792448 | 0.71 | EPHX2 (0.56) | EPHX2MAPK1DPP8DPP9 | |
| SCHEMBL17344416 | 0.70 | EPHX2 (0.49) | EPHX2 | |
| SCHEMBL3793395 | 0.69 | EPHX2 (0.83) | EPHX2MAPK1DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112946-A1 | ADAMANTANE BISUREA DERIVATIVES, METHOD OF PREPARATION AND APPLICATION IN ANION SENSING | RUDJER BOSKOVIC INSTITUTE (HR) | 2010-10-07 | — | — | WO | disclosed |