Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796561 | 0.96 | EPHX2 (0.58) | EPHX2MEN1NPC1LMNATP53 | |
| SCHEMBL3794376 | 0.81 | EPHX2 (0.51) | EPHX2RAB9A | |
| SCHEMBL3790735 | 0.80 | EPHX2 (0.54) | EPHX2MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3793044 | 0.76 | EPHX2 (0.60) | EPHX2MEN1NPC1MAPTRAB9A | |
| SCHEMBL3799290 | 0.75 | EPHX2 (0.58) | EPHX2MEN1MAPTRAB9AKMT2A | |
| SCHEMBL3808293 | 0.74 | EPHX2 (0.47) | EPHX2RAB9A | |
| SCHEMBL3792448 | 0.73 | EPHX2 (0.56) | EPHX2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL1420838 | 0.73 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL3788548 | 0.72 | KDM4E (0.50) | EPHX2MAPTRAB9A | |
| SCHEMBL11525691 | 0.72 | MAPT (0.55) | EPHX2MEN1NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112946-A1 | ADAMANTANE BISUREA DERIVATIVES, METHOD OF PREPARATION AND APPLICATION IN ANION SENSING | RUDJER BOSKOVIC INSTITUTE (HR) | 2010-10-07 | — | — | WO | disclosed |