Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | GCLC | P48506 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Taurine SCHEMBL4898461 | 0.94 | LMNA (0.54) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL4898456 | 0.94 | LMNA (0.54) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL27979344 | 0.87 | LMNA (0.61) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL30443868 | 0.87 | LMNA (0.61) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL27979203 | 0.85 | LMNA (0.58) | LMNASLC6A6CYP2C19BLMAPP | |
| Threonine SCHEMBL16341775 | 0.84 | LMNA (0.52) | LMNASLC6A6CYP2C19BLMAPP | |
| Threonine SCHEMBL16341774 | 0.84 | LMNA (0.52) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL9069180 | 0.82 | LMNA (0.67) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL28014699 | 0.82 | LMNA (0.54) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL17801096 | 0.81 | LMNA (0.74) | LMNASLC6A6CYP2C19BLMAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252292-A2 | CARDIOPLEGIA SOLUTION FOR CARDIAC SURGERY | President and Fellows of Harvard College (US) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009105165-A2 | CARDIOPLEGIA SOLUTION FOR CARDIAC SURGERY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-08-27 | — | — | WO | disclosed |