Taurine

Taurine

SCHEMBL17801096

CC(=O)O.NCCS(=O)(=O)O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Taurine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.74
BLM P54132 2/20 0.74
SLC6A6 P31641 1/20 0.74
CYP2C19 P33261 1/20 0.74
APP P05067 1/20 0.52
PTGS1 P23219 1/20 0.38
PDE4A P27815 1/20 0.38
FFAR3 O14843 1/20 0.37
LCK P06239 1/20 0.37
FYN P06241 1/20 0.37
KDM4E B2RXH2 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PAOX Q6QHF9 4/20 0.33
GABRR1 P24046 3/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
GLRA1 P23415 1/20 0.32
SLC6A9 P48067 1/20 0.32
OR51E2 Q9H255 1/20 0.32
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taurine SCHEMBL3152449 1.00 LMNA (0.74) LMNABLMSLC6A6CYP2C19APP
Taurine SCHEMBL21051780 0.90 LMNA (0.67) LMNABLMSLC6A6CYP2C19APP
Taurine SCHEMBL4449607 0.89 LMNA (0.82) LMNABLMSLC6A6CYP2C19APP
Taurine SCHEMBL27814625 0.86 LMNA (0.78) LMNABLMSLC6A6CYP2C19APP
Taurine SCHEMBL28062289 0.86 LMNA (0.61) LMNABLMSLC6A6CYP2C19APP
Taurine SCHEMBL29931159 0.86
Taurine SCHEMBL28148201 0.86
Taurine SCHEMBL23068 0.86
Taurine SCHEMBL30179154 0.86
Taurine SCHEMBL30191395 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11015152-B2 Cleansing bars with taurine COLGATE-PALMOLIVE COMPANY (US) 2021-05-25 US claimed
CN-108713054-B Cleansing bar containing taurine 高露洁-棕榄公司 2020-09-29 CN claimed
EP-3383984-B1 CLEANSING BARS WITH TAURINE COLGATE PALMOLIVE CO (US) 2020-03-11 EP claimed
EP-3220879-B1 CLEANSING BARS WITH TAURINE COLGATE PALMOLIVE CO (US) 2020-03-04 EP claimed
CN-107001999-B Cleansing bar containing taurine 高露洁-棕榄公司 2020-02-07 CN claimed
US-10400199-B2 Cleansing bars with taurine COLGATE-PALMOLIVE COMPANY (US) 2019-09-03 US claimed
US-20180355293-A1 Cleansing Bars with Taurine COLGATE-PALMOLIVE COMPANY (US) 2018-12-13 US claimed
CN-108713054-A Cleansing bars containing taurine 高露洁-棕榄公司 2018-10-26 CN claimed
EP-3383984-A1 CLEANSING BARS WITH TAURINE Colgate-Palmolive Company (US) 2018-10-10 EP claimed
US-20170335251-A1 Cleansing Bars with Taurine COLGATE-PALMOLIVE COMPANY (US) 2017-11-23 US claimed
EP-3220879-A1 CLEANSING BARS WITH TAURINE Colgate-Palmolive Company (US) 2017-09-27 EP claimed
CN-107001999-A Cleansing bar containing taurine 高露洁-棕榄公司 2017-08-01 CN claimed
WO-2017095445-A1 CLEANSING BARS WITH TAURINE COLGATE-PALMOLIVE COMPANY (US) 2017-06-08 WO claimed
WO-2016089422-A1 CLEANSING BARS WITH TAURINE COLGATE-PALMOLIVE COMPANY (US) 2016-06-09 WO claimed
EP-4676430-A1 HYDROXY ACIDS FOR SCALP AND HAIR IN SULFATE FREE PERSONAL CARE COMPOSITIONS The Procter & Gamble Company (US) 2026-01-14 EP disclosed
WO-2024187061-A1 HYDROXY ACIDS FOR SCALP AND HAIR IN SULFATE FREE PERSONAL CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2024-09-12 WO disclosed
US-20240299275-A1 HYDROXY ACIDS FOR SCALP AND HAIR IN SULFATE FREE PERSONAL CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2024-09-12 US disclosed
WO-2017095445-A1 CLEANSING BARS WITH TAURINE COLGATE-PALMOLIVE COMPANY (US) 2017-06-08 WO disclosed
WO-2016106071-A1 ORAL CARE COMPOSITION COLGATE-PALMOLIVE COMPANY (US) 2016-06-30 WO disclosed
WO-2016089422-A1 CLEANSING BARS WITH TAURINE COLGATE-PALMOLIVE COMPANY (US) 2016-06-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240299275-A1 HYDROXY ACIDS FOR SCALP AND HAIR IN SULFATE FREE PERSONAL CARE COMPOSITIONS HAO2, SCO2, POLR1C LMNA 3460/4885BLM 2698/4885SLC6A6 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.