Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29022789 | 0.84 | LMNA (0.34) | LMNASLC6A6CYP2C19BLMGABRR1 | |
| SCHEMBL16341776 | 0.83 | LMNA (0.31) | LMNASLC6A6CYP2C19BLM | |
| SCHEMBL8200267 | 0.81 | TP53 (0.33) | LMNACYP2C19 | |
| SCHEMBL27596902 | 0.80 | DPP4 (0.36) | — | |
| SCHEMBL1154473 | 0.79 | LMNA (0.37) | LMNASLC6A6CYP2C19BLM | |
| SCHEMBL2015093 | 0.78 | LMNA (0.33) | LMNASLC6A6CYP2C19BLM | |
| SCHEMBL31324268 | 0.78 | LMNA (0.34) | LMNASLC6A6CYP2C19BLM | |
| SCHEMBL5164474 | 0.77 | PTGS1 (0.39) | LMNASLC6A6CYP2C19BLM | |
| SCHEMBL28257351 | 0.76 | GSR (0.41) | LMNASLC6A6CYP2C19BLM | |
| SCHEMBL8741229 | 0.76 | GABRR1 (0.32) | LMNASLC6A6CYP2C19BLMGABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252292-A2 | CARDIOPLEGIA SOLUTION FOR CARDIAC SURGERY | President and Fellows of Harvard College (US) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009105165-A2 | CARDIOPLEGIA SOLUTION FOR CARDIAC SURGERY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-08-27 | — | — | WO | disclosed |