SCHEMBL1154473

SCHEMBL1154473

NCCS(=O)(=O)OC(=O)C(O)C(O)C(=O)OS(=O)(=O)CCN

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
SLC6A6 P31641 1/20 0.37
CYP2C19 P33261 1/20 0.37
BLM P54132 1/20 0.37
HTT P42858 1/20 0.31
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1154476 0.92 TSHR (0.37) LMNASLC6A6CYP2C19BLM
SCHEMBL29022789 0.83 LMNA (0.34) LMNASLC6A6CYP2C19BLM
SCHEMBL17024357 0.82 PDE4A (0.43) LMNA
SCHEMBL3799351 0.79 LMNA (0.34) LMNASLC6A6CYP2C19BLM
SCHEMBL16341776 0.79 LMNA (0.31) LMNASLC6A6CYP2C19BLM
SCHEMBL2015093 0.78 LMNA (0.33) LMNASLC6A6CYP2C19BLM
SCHEMBL27814624 0.77 LMNA (0.43) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL8741229 0.75 GABRR1 (0.32) LMNASLC6A6CYP2C19BLM
SCHEMBL28257351 0.75 GSR (0.41) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL21295188 0.75 LMNA (0.42) LMNASLC6A6CYP2C19BLMAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090304620-A1 HAIR TREATMENT PRODUCTS COMPRISING POLYMERS HENKEL AG & CO. KGAA (DE) 2009-12-10 US claimed
US-10722439-B2 Hair care products HENKEL AG & CO. KGAA (DE) 2020-07-28 US disclosed
US-20200170912-A1 COMPOSITION FOR THE CARE OF HUMAN HAIR HENKEL AG & CO. KGAA (DE) 2020-06-04 US disclosed
US-10328007-B2 Hair straightening with carbocisteine HENKEL AG & CO. KGAA (DE) 2019-06-25 US disclosed
US-20190021968-A1 HAIR CARE PRODUCTS HENKEL AG & CO. KGAA (DE) 2019-01-24 US disclosed
US-20160296441-A1 CONDITIONER FOR KERATIN FIBERS HAVING A SILICONE SUBSTITUTE HENKEL AG & CO. KGAA (DE) 2016-10-13 US disclosed
US-9456976-B2 Hair treatment compositions comprising selected UV filters and selected complexes of acidic protein hydrolysates and basic fatty acid amidoamines HENKEL AG & CO. KGAA (DE) 2016-10-04 US disclosed
US-20160263000-A1 HAIR STRAIGHTENING WITH CARBOCISTEINE HENKEL AG & CO. KGAA (DE) 2016-09-15 US disclosed
US-9248087-B2 Anti-dandruff hair care products with selective active ingredients and a cationic keratin HENKEL AG & CO. KGAA (DE) 2016-02-02 US disclosed
US-9211315-B2 Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminoglycanases HALOZYME, INC. (US) 2015-12-15 US disclosed
US-20140121174-A1 ANTI-DANDRUFF HAIR CARE PRODUCTS WITH SELECTIVE ACTIVE INGREDIENTS AND A CATIONIC KERATIN HENKEL AG & CO. KGAA (DE) 2014-05-01 US disclosed
US-20140120050-A1 ANTI-DRANDRUFF HAIR CARE PRODUCTS WITH SELECTIVE ACTIVE INGREDIENTS AND A CATIONIC KERATIN HENKEL AG & CO. KGAA (DE) 2014-05-01 US disclosed
US-20130125914-A1 HAIR-CONDITIONING COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2013-05-23 US disclosed
US-20120204895-A1 HAIR TREATMENT AGENTS COMPRISING POLYQUATERNIUM-72 HENKEL AG & CO. KGAA (DE) 2012-08-16 US disclosed
US-20120171149-A1 AGENTS FOR TREATING KERATIN FIBERS, CONTAINING DIMETHYLSILANOL HYALURONATES AND GLYCEROL HENKEL AG & CO. KGAA (DE) 2012-07-05 US disclosed
US-20120121529-A1 HAIR CONDITIONERS COMPRISING SELECTED CATIONIC SILICONES AND DIMETHICONE HENKEL AG & CO. KGAA (DE) 2012-05-17 US disclosed
US-20120114586-A1 HAIR CONDITIONERS COMPRISING SELECTED CATIONIC SILICONES AND A B SERIES VITAMIN HENKEL AG & CO. KGAA (DE) 2012-05-10 US disclosed
US-20110268684-A1 HAIR CONDITIONERS COMPRISING IMIDAZOLINES AND ESTER OILS HENKEL AG & CO. KGAA (DE) 2011-11-03 US disclosed
US-20110033407-A1 Hair Treatment Means With Cloudberry Extract HENKEL AG & CO. KGAA (DE) 2011-02-10 US disclosed
US-20090304620-A1 HAIR TREATMENT PRODUCTS COMPRISING POLYMERS HENKEL AG & CO. KGAA (DE) 2009-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (16 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10722439-B2 Hair care products ACMSD, ARG1, NACA LMNA 608/4885SLC6A6 1302/4885CYP2C19 2826/4885
US-20120204895-A1 HAIR TREATMENT AGENTS COMPRISING POLYQUATERNIUM-72 HTT, AAAS, HNMT LMNA 1332/4885SLC6A6 1179/4885CYP2C19 4299/4885
US-20120171149-A1 AGENTS FOR TREATING KERATIN FIBERS, CONTAINING DIMETHYLSILANOL HYALURONATES AND GLYCEROL KRT18, CD44, DSG1 LMNA 1541/4885SLC6A6 2380/4885CYP2C19 4846/4885
US-20110268684-A1 HAIR CONDITIONERS COMPRISING IMIDAZOLINES AND ESTER OILS PLIN3, PLIN5, FABP4 LMNA 2270/4885SLC6A6 4360/4885CYP2C19 394/4885
US-20090304620-A1 HAIR TREATMENT PRODUCTS COMPRISING POLYMERS ASS1, SRM, COL1A1 LMNA 2570/4885SLC6A6 3139/4885CYP2C19 824/4885
US-20120121529-A1 HAIR CONDITIONERS COMPRISING SELECTED CATIONIC SILICONES AND DIMETHICONE KRT18, DNER, DSC1 LMNA 487/4885SLC6A6 2972/4885CYP2C19 2815/4885
US-20140121174-A1 ANTI-DANDRUFF HAIR CARE PRODUCTS WITH SELECTIVE ACTIVE INGREDIENTS AND A CATIONIC KERATIN KRT18, ALG1, PIGO LMNA 884/4885SLC6A6 3490/4885CYP2C19 4018/4885
US-20110033407-A1 Hair Treatment Means With Cloudberry Extract KRT18, TUBB8, TUBB6 LMNA 1046/4885SLC6A6 2830/4885CYP2C19 3091/4885
US-20190021968-A1 HAIR CARE PRODUCTS ACMSD, ARG1, NACA LMNA 658/4885SLC6A6 1073/4885CYP2C19 2810/4885
US-10328007-B2 Hair straightening with carbocisteine KRT18, PRKDC, PRKACG LMNA 303/4885SLC6A6 1939/4885CYP2C19 4534/4885
US-20120114586-A1 HAIR CONDITIONERS COMPRISING SELECTED CATIONIC SILICONES AND A B SERIES VITAMIN KRT18, PROC, BTD LMNA 240/4885SLC6A6 1146/4885CYP2C19 3644/4885
US-20160296441-A1 CONDITIONER FOR KERATIN FIBERS HAVING A SILICONE SUBSTITUTE KRT18, CUTA, DNER LMNA 1490/4885SLC6A6 2912/4885CYP2C19 4324/4885
US-20140120050-A1 ANTI-DRANDRUFF HAIR CARE PRODUCTS WITH SELECTIVE ACTIVE INGREDIENTS AND A CATIONIC KERATIN KRT18, EBP, DSG1 LMNA 897/4885SLC6A6 3182/4885CYP2C19 4746/4885
US-20130125914-A1 HAIR-CONDITIONING COMPOSITIONS SHH, HDAC10, NR5A1 LMNA 3449/4885SLC6A6 2021/4885CYP2C19 3464/4885
US-20200170912-A1 COMPOSITION FOR THE CARE OF HUMAN HAIR POLR1C, KRT18, SLC27A1 LMNA 1447/4885SLC6A6 542/4885CYP2C19 2817/4885
US-20160263000-A1 HAIR STRAIGHTENING WITH CARBOCISTEINE KRT18, PRKDC, PRKACG LMNA 303/4885SLC6A6 1939/4885CYP2C19 4534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.