SCHEMBL3799375

SCHEMBL3799375

CC(C)NC(=O)[C@H]1CC[C@H](CN)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLG P00747 3/20 0.52
PLAT P00750 1/20 0.52
LMNA P02545 1/20 0.52
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
F11 P03951 6/20 0.43
AOC2 O75106 1/20 0.43
KLKB1 P03952 4/20 0.43
PLAU P00749 2/20 0.43
TP53 P04637 1/20 0.42
CHRNB2 P17787 1/20 0.42
CHRNB4 P30926 1/20 0.42
CHRNA3 P32297 1/20 0.42
CHRNA7 P36544 1/20 0.42
CHRNA4 P43681 1/20 0.42
PRSS1 P07477 2/20 0.42
PRSS2 P07478 2/20 0.42
PRSS3 P35030 2/20 0.42
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10076786 0.84 SMN1; SMN2 (0.60) LMNAMEN1KMT2ASMN1; SMN2CHRNB2
SCHEMBL172134 0.84
SCHEMBL17029402 0.83 MEN1 (0.49) MEN1KMT2ASMN1; SMN2AOC2TP53
SCHEMBL17518760 0.83 MEN1 (0.49) MEN1KMT2ASMN1; SMN2AOC2TP53
SCHEMBL620977 0.83 SMN1; SMN2 (0.49) LMNAMEN1KMT2ASMN1; SMN2AOC2
SCHEMBL21501965 0.81 MEN1 (0.47) LMNAMEN1KMT2ASMN1; SMN2AOC2
SCHEMBL26707070 0.81 MEN1 (0.47) LMNAMEN1KMT2ASMN1; SMN2AOC2
SCHEMBL24275989 0.79 SMN1; SMN2 (0.51) LMNAMEN1KMT2ASMN1; SMN2CHRNB2
SCHEMBL1652727 0.79 PLG (0.57) PLGPLATLMNAMEN1KMT2A
SCHEMBL20740187 0.79 SMN1; SMN2 (0.51) LMNAMEN1KMT2ASMN1; SMN2CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100292509-A1 VEGFC PRODUCTION PROMOTER SHISEIDO COMPANY, LTD 2010-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292509-A1 VEGFC PRODUCTION PROMOTER VEGFA, PGF, FLT1 PLG 9/4885PLAT 74/4885LMNA 1782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.