Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12461257 | 0.96 | PPARA (0.51) | PPARANOS2MAPTRECQLKCNH2 | |
| SCHEMBL7504627 | 0.94 | PPARA (0.54) | PPARANOS2MAPTRECQLKCNH2 | |
| SCHEMBL25970261 | 0.94 | PPARA (0.54) | PPARANOS2MAPTRECQLKCNH2 | |
| SCHEMBL7356165 | 0.87 | — | — | |
| SCHEMBL9666153 | 0.82 | MAPT (0.39) | PPARAMAPTRECQLALDH1A1TRPM8 | |
| SCHEMBL6391920 | 0.82 | PPARA (0.40) | PPARAMAPTRECQLALDH1A1TRPM8 | |
| SCHEMBL8977882 | 0.82 | ALDH1A1 (0.40) | PPARAMAPTRECQLALDH1A1TRPM8 | |
| SCHEMBL8977881 | 0.82 | MAPT (0.39) | PPARAMAPTRECQLALDH1A1TRPM8 | |
| SCHEMBL18256058 | 0.82 | ALDH1A1 (0.40) | PPARAMAPTRECQLALDH1A1TRPM8 | |
| SCHEMBL18256162 | 0.82 | MAPT (0.39) | PPARAMAPTRECQLALDH1A1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023199940-A1 | LIQUID COMPOSITION | 花王株式会社 | 2023-10-19 | — | — | WO | disclosed |
| CN-107108658-A | Substituted cyclic pyrimidines and their use | 拜耳医药股份有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-104955823-A | Carboxy-substituted imidazo [1,2-a ] pyridinecarboxamides and their use as stimulators of soluble guanylate cyclase | Bayer Pharma AG | 2015-09-30 | — | — | CN | disclosed |
| CN-101910229-B | Onium salt-containing polymer | NIPPON SODA CO | 2013-01-30 | — | — | CN | disclosed |
| EP-2398782-A1 | ISOXAZOLE-ISOXAZOLE AND ISOXAZOLE-ISOTHIAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-12-28 | — | — | EP | disclosed |
| CN-101910229-A | Onium salt-containing polymer | NIPPON SODA CO | 2010-12-08 | — | — | CN | disclosed |
| WO-2010094669-A1 | ISOXAZOLE-ISOXAZOLE AND ISOXAZOLE-ISOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-08-26 | — | — | WO | disclosed |
| EP-2130820-A1 | Antipruritics | SHIONOGI & CO., LTD. (JP) | 2009-12-09 | — | — | EP | disclosed |
| EP-1477186-B1 | ANTIPRURITICS | SHIONOGI & CO (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-7446195-B2 | High affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | SCHERING CORPORATION | 2007-02-22 | — | — | US | disclosed |
| WO-2006056930-A2 | NOVEL 4 -AMINOPIPERIDINE DERIVATIVES AS PLASMEPSIN II INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-06-01 | — | — | WO | disclosed |
| CN-1200932-C | Substituted phenylcyclohexane carboxylic acid amides that have an adenosine uptake inhibiting effect | BAYER AG (DE) | 2005-05-11 | — | — | CN | disclosed |
| CN-1365356-A | Substituted phenylcyclohexane carboxylic acid amides that have an adenosine uptake inhibiting effect | BAYER AG (DE) | 2002-08-21 | — | — | CN | disclosed |
| CN-1145075-A | Antagonist's of endothelin receptors | JAPAT LTD (CH) | 1997-03-12 | — | — | CN | disclosed |
| CN-1097745-A | The piperazine that replaces | BAYER AG (DE) | 1995-01-25 | — | — | CN | disclosed |
| CN-1086809-A | 5-oxo-dibenzo [a, d] ring heptan-1, the 4-diene | BAYER AG (DE) | 1994-05-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043045-A1 | Novel high affinity thiophene-based and furan-based kinase ligands | CDKL2, CDK2, CDKL1 | PPARA 3041/4885NOS2 3934/4885MAPT 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.