Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504627 | 1.00 | PPARA (0.54) | PPARAKCNH2MAPTRECQLPTGS2 | |
| SCHEMBL12461257 | 0.98 | PPARA (0.51) | PPARAKCNH2MAPTRECQLPTGS2 | |
| SCHEMBL3799442 | 0.94 | PPARA (0.47) | PPARAKCNH2MAPTRECQLNOS2 | |
| SCHEMBL7356165 | 0.85 | — | — | |
| SCHEMBL22224155 | 0.83 | PPARA (0.40) | PPARAKCNH2MAPTRECQLALDH1A1 | |
| SCHEMBL9666337 | 0.82 | PPARA (0.42) | PPARAMAPTRECQLALDH1A1 | |
| SCHEMBL9666299 | 0.82 | PPARA (0.39) | PPARAMAPTRECQLALDH1A1 | |
| SCHEMBL9728964 | 0.81 | PPARA (0.51) | PPARAKCNH2PTGS2NOS2ALDH1A1 | |
| SCHEMBL9728758 | 0.81 | PPARA (0.51) | PPARAKCNH2PTGS2NOS2ALDH1A1 | |
| SCHEMBL9729219 | 0.81 | PPARA (0.51) | PPARAKCNH2PTGS2NOS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257396-A1 | MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS INC (US) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257396-A1 | MACROCYCLES AND THEIR USE | VHL, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DLD | PPARA 1961/4885KCNH2 4303/4885MAPT 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.