SCHEMBL3799495

SCHEMBL3799495

CCCC(Cl)/C=C\C(Cl)CCC

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3799500 1.00 TSHR (0.30) TSHR
SCHEMBL11278757 1.00 TSHR (0.30) TSHR
SCHEMBL11279107 0.91
SCHEMBL11279110 0.91
SCHEMBL11286270 0.89 TSHR (0.31) TSHR
SCHEMBL11283436 0.89 DNM1 (0.36) TSHR
SCHEMBL11283418 0.89 DNM1 (0.36) TSHR
SCHEMBL11286275 0.89 TSHR (0.31) TSHR
SCHEMBL11281155 0.87 OPRM1 (0.39) TSHR
SCHEMBL11281151 0.87 OPRM1 (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100022792-A1 SYNTHETIC PROCESS FOR CYCLIC ORGANOSILANES GROSS, PHILIP M. 2010-01-28 US disclosed
EP-2086986-A2 SYNTHETIC PROCESS FOR CYCLIC ORGANOSILANES Starfire Systems, Inc. (US) 2009-08-12 EP disclosed
WO-2008033980-A2 SYNTHETIC PROCESS FOR CYCLIC ORGANOSILANES STARFIRE SYSTEMS, INC. (US) 2008-03-20 WO disclosed