Carbazole

Carbazole

SCHEMBL3799711

CCCCCCCCCCCC(=O)Br.c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.53
MGAM O43451 1/20 0.53
SI P14410 1/20 0.53
MGAM2 Q2M2H8 1/20 0.53
ALDH1A1 P00352 6/20 0.52
KDM4E B2RXH2 5/20 0.52
HPGD P15428 5/20 0.52
HSD17B10 Q99714 3/20 0.52
GSK3B P49841 1/20 0.49
OXER1 Q8TDS5 1/20 0.49
MAPT P10636 2/20 0.48
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
GABRA2 P47869 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbazole SCHEMBL9398513 0.86 OXER1 (0.64) GAAMGAMSIMGAM2ALDH1A1
Palmitic Acid SCHEMBL9397126 0.86 OXER1 (0.64) GAAMGAMSIMGAM2ALDH1A1
Carbazole SCHEMBL28847016 0.84 OXER1 (0.61) GAAMGAMSIMGAM2ALDH1A1
Tetradecane SCHEMBL9931701 0.83 ALDH1A1 (0.64) GAAALDH1A1KDM4EHPGDHSD17B10
Carbazole SCHEMBL27757289 0.81 ALDH1A1 (0.67) GAAALDH1A1KDM4EHPGDHSD17B10
Carbazole SCHEMBL27643881 0.79 ALDH1A1 (0.64) GAAALDH1A1KDM4EHPGDHSD17B10
SCHEMBL22279067 0.79 KDM4E (0.58) GAAMGAMSIMGAM2ALDH1A1
Carbazole SCHEMBL28851972 0.78 ALDH1A1 (0.52) GAAALDH1A1KDM4EHPGDHSD17B10
Carbazole SCHEMBL4314436 0.76 GABRP (0.55) GAAALDH1A1KDM4EHPGDHSD17B10
Acridone SCHEMBL28159674 0.76 KDM4E (0.69) GAAALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109913455-B Small interfering RNA capable of treating cancer 左志军 2024-05-28 CN disclosed
CN-117987412-A SiRNA for inhibiting STAT3 gene expression 成都先衍生物技术有限公司 2024-05-07 CN disclosed
CN-117987413-A SARNA for targeting CEBPA gene expression and application thereof 成都先衍生物技术有限公司 2024-05-07 CN disclosed
EP-2217208-A2 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION Otsuka Pharmaceutical Co., Ltd. (JP) 2010-08-18 EP disclosed
WO-2009061003-A2 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-05-14 WO disclosed