Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 15/20 | 0.59 |
| ▸ | ITGB1 | P05556 | 14/20 | 0.59 |
| ▸ | MMP1 | P03956 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404783 | 0.82 | ACE (0.56) | ITGA4ITGB1MMP1MMEACE | |
| SCHEMBL7404784 | 0.82 | ACE (0.56) | ITGA4ITGB1MMP1MMEACE | |
| SCHEMBL7404786 | 0.82 | ACE (0.56) | ITGA4ITGB1MMP1MMEACE | |
| SCHEMBL16294576 | 0.80 | ITGB1 (0.60) | ITGA4ITGB1MMP1MME | |
| SCHEMBL11817182 | 0.75 | ITGA4 (0.52) | ITGA4ITGB1MMP1L3MBTL1ITGB7 | |
| SCHEMBL11817192 | 0.75 | ITGA4 (0.52) | ITGA4ITGB1MMP1L3MBTL1ITGB7 | |
| SCHEMBL11871291 | 0.75 | ITGA4 (0.52) | ITGA4ITGB1MMP1ITGB7 | |
| SCHEMBL11871302 | 0.75 | ITGA4 (0.52) | ITGA4ITGB1MMP1ITGB7 | |
| SCHEMBL26993362 | 0.75 | LMNA (0.60) | L3MBTL1MMP2MMEACECPA1 | |
| SCHEMBL27555413 | 0.75 | ITGB1 (0.51) | ITGA4ITGB1MMP1L3MBTL1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128092-A1 | ANTI-IL1-β ANTIBODY COMBINATION THERAPY | NOVARTIS AG (CH) | 2010-11-11 | — | — | WO | disclosed |