Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | ACP1 | P24666 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | PNPO | Q9NVS9 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | PDXK | O00764 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | YWHAG | P61981 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2692050 | 0.84 | P2RX2 (0.56) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL3392576 | 0.79 | P2RX2 (0.53) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL4576456 | 0.77 | ESR1 (0.52) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL8835556 | 0.75 | KDM4E (0.59) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL17224491 | 0.72 | KDM4E (0.56) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL6045299 | 0.71 | KDM4E (0.54) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL2467030 | 0.71 | KDM4E (0.54) | P2RX2ESR1PTGS1ACP1PDE4A | |
| Pyridoxal Phosphate Anhydrous SCHEMBL29362986 | 0.70 | P2RX2 (1.00) | P2RX2ESR1PTGS1ACP1PDE4A | |
| Pyridoxal Phosphate Anhydrous SCHEMBL23158 | 0.70 | P2RX2 (1.00) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL14687825 | 0.70 | KDM4E (0.53) | P2RX2ESR1PTGS1ACP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197566-A1 | Method and Apparatus for Preparing an Acellular Red Blood Cell Substitute | NORTHFIELD LABORATORIES, INC. | 2010-08-05 | — | — | US | disclosed |
| US-7521417-B2 | Method and apparatus for preparing an acellular red blood cell substitute | NORTHFIELD LABORATORIES, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| US-7411044-B2 | Polymerized hemoglobin solutions having reduced amounts of tetramer and method for preparing | NORTHFIELD LABORATORIES, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| US-20080108555-A1 | Method and Apparatus for Preparing an Acellular Red Blood Cell Substitute | NORTHFIELD LABORATORIES, INC. | 2008-05-08 | — | — | US | disclosed |
| US-20060287222-A1 | Polymerized hemoglobin solutions having reduced amounts of tetramer and method for preparing | NORTHFIELD LABORATORIES, INC. (US) | 2006-12-21 | — | — | US | disclosed |
| US-7135553-B2 | Polymerized hemoglobin solutions having reduced amounts of tetramer and method for preparing | NORTHFIELD LABORATORIES, INC. (US) | 2006-11-14 | — | — | US | disclosed |
| US-20050065067-A1 | Method and apparatus for preparing an acellular red blood cell substitute | NORTHFIELD LABORATORIES, INC. | 2005-03-24 | — | — | US | disclosed |
| US-20040186047-A1 | Polymerized hemoglobin solutions having reduced amounts of tetramer and method for preparing | NORTHFIELD LABORATORIES (US) | 2004-09-23 | — | — | US | disclosed |
| US-20030191050-A1 | Method and apparatus for preparing an acellular read blood cell substitute | NORTHFIELD LABORATORIES, INC. | 2003-10-09 | — | — | US | disclosed |
| EP-0928294-B1 | METHOD AND APPARATUS FOR PREPARING AN ACELLULAR RED BLOOD CELL SUBSTITUTE | NORTHFIELD LAB (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-1308460-A2 | Method and apparatus for preparing an acellular red blood cell substitute | NORTHFIELD LABORATORIES, INC. (US) | 2003-05-07 | — | — | EP | disclosed |
| US-6498141-B2 | FOR INFUSING INTO HUMAN PATIENTS | NORTHFIELD LABORATORIES, INC. | 2002-12-24 | — | — | US | disclosed |
| US-20020025343-A1 | METHOD AND APPARATUS FOR PREPARING AN ACELLULAR RED BLOOD CELL SUBSTITUTE | NORTHFIELD LIQUIDATION TRUST | 2002-02-28 | — | — | US | disclosed |
| EP-0928294-A1 | METHOD AND APPARATUS FOR PREPARING AN ACELLULAR RED BLOOD CELL SUBSTITUTE | NORTHFIELD LABORATORIES, INC. (US) | 1999-07-14 | — | — | EP | disclosed |
| WO-1997035883-A1 | METHOD AND APPARATUS FOR PREPARING AN ACELLULAR RED BLOOD CELL SUBSTITUTE | NORTHFIELD LABORATORIES, INC. (US) | 1997-10-02 | — | — | WO | disclosed |
| US-5464814-A | Polymerized, pyridoxylated hemoglobin | NORTHFIELD LABORATORIES, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| WO-1990013309-A1 | A HEMOGLOBIN COMPOSITION AND ITS USE | STAAT DER NEDERLANDEN, DE MINISTER VAN DEFENSIE, VOOR DEZE: HET HOOFD VAN DE AFDELING MILITAIR GENEESKUNDIG BELEID (NL) | 1990-11-15 | — | — | WO | disclosed |