Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | ACP1 | P24666 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | PNPO | Q9NVS9 | 1/20 | 0.36 |
| ▸ | PDXK | O00764 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | YWHAG | P61981 | 1/20 | 0.33 |
| ▸ | YWHAZ | P63104 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2692050 | 0.80 | P2RX2 (0.56) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL3800949 | 0.79 | P2RX2 (0.54) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL9717089 | 0.74 | ESR1 (0.44) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL4576456 | 0.73 | ESR1 (0.52) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL8835556 | 0.71 | KDM4E (0.59) | P2RX2ESR1PTGS1ACP1PDE4A | |
| Pyridoxal Phosphate Anhydrous SCHEMBL29362986 | 0.69 | P2RX2 (1.00) | P2RX2ESR1PTGS1ACP1PDE4A | |
| Pyridoxal Phosphate Anhydrous SCHEMBL23158 | 0.69 | P2RX2 (1.00) | P2RX2ESR1PTGS1ACP1PDE4A | |
| SCHEMBL17224491 | 0.69 | KDM4E (0.56) | P2RX2ESR1PTGS1ACP1PDE4A | |
| Pyridoxal Phosphate Anhydrous SCHEMBL20335516 | 0.69 | P2RX2 (0.97) | P2RX2ESR1PTGS1ACP1PDE4A | |
| Pyridoxal Phosphate Anhydrous SCHEMBL20335524 | 0.69 | P2RX2 (0.97) | P2RX2ESR1PTGS1ACP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940841-B9 | COMPOUNDS COMPRISING A BIOLOGICAL TARGET RECOGNIZING PART, COUPLED TO A SIGNAL PART CAPABLE OF COMPLEXING GALLIUM | GUERBET SA (FR) | 2017-04-19 | — | — | EP | disclosed |
| EP-1940841-B1 | COMPOUNDS COMPRISING A BIOLOGICAL TARGET RECOGNIZING PART, COUPLED TO A SIGNAL PART CAPABLE OF COMPLEXING GALLIUM | GUERBET SA (FR) | 2016-12-07 | — | — | EP | disclosed |
| EP-1796738-B1 | BICYCLAM CONJUGATE FOR MRI AND SCINTIGRAPHY OF DISEASES ASSOCIATED WITH THE CXCR4 RECEPTOR | GUERBET SA (FR) | 2013-08-07 | — | — | EP | disclosed |
| EP-2396040-A1 | USE OF BUFFERS FOR RADIONUCLIDE COMPLEXATION | GUERBET (FR) | 2011-12-21 | — | — | EP | disclosed |
| EP-1635878-B1 | PEPTIDE CONJUGATE FOR MAGNETIC RESONANCE IMAGING OF MATRIX METALLOPROTEINASES | GUERBET SA (FR) | 2010-12-29 | — | — | EP | disclosed |
| WO-2010092114-A1 | USE OF BUFFERS FOR RADIONUCLIDE COMPLEXATION | GUERBET (FR) | 2010-08-19 | — | — | WO | disclosed |
| EP-1940841-A2 | COMPOUNDS COMPRISING A BIOLOGICAL TARGET RECOGNIZING PART, COUPLED TO A SIGNAL PART CAPABLE OF COMPLEXING GALLIUM | GUERBET (FR) | 2008-07-09 | — | — | EP | disclosed |
| EP-1796738-A2 | DIAGNOSTIC COMPOUNDS FOR TARGETING A CHEMOKINE RECEPTOR | GUERBET (FR) | 2007-06-20 | — | — | EP | disclosed |
| WO-2007042504-A2 | COMPOUNDS COMPRISING A BIOLOGICAL TARGET RECOGNIZING PART, COUPLED TO A SIGNAL PART CAPABLE OF COMPLEXING GALLIUM | GUERBET (FR) | 2007-04-19 | — | — | WO | disclosed |
| WO-2006032704-A2 | DIAGNOSTIC COMPOUNDS FOR TARGETING A CHEMOKINE RECEPTOR | GUERBET (FR) | 2006-03-30 | — | — | WO | disclosed |
| EP-1635878-A2 | PEPTIDE CONJUGATE FOR MAGNETIC RESONANCE IMAGING | GUERBET (FR) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004112840-A2 | PEPTIDE CONJUGATE FOR MAGNETIC RESONANCE IMAGING | GUERBET (FR) | 2004-12-29 | — | — | WO | disclosed |