Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25268918 | 0.88 | FFAR3 (0.44) | FFAR3ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL25269622 | 0.88 | FFAR3 (0.44) | FFAR3ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL7018317 | 0.88 | FFAR3 (0.44) | FFAR3ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL3057470 | 0.86 | FFAR3 (0.59) | FFAR3HTR2AHTR2CHRH1HTR2B | |
| SCHEMBL13737602 | 0.83 | FFAR3 (0.34) | FFAR3ALDH1A1MAPK1CYP2C19OPRM1 | |
| SCHEMBL27711332 | 0.81 | FFAR3 (0.50) | FFAR3ALDH1A1MAPK1CYP2C19NPSR1 | |
| SCHEMBL1468595 | 0.80 | USP2 (0.36) | FFAR3ALDH1A1MAPK1CYP2C19NPSR1 | |
| SCHEMBL3952636 | 0.79 | SPR (0.41) | FFAR3ALDH1A1MAPK1CYP2C19OPRM1 | |
| SCHEMBL12373947 | 0.76 | USP2 (0.45) | FFAR3 | |
| SCHEMBL17469418 | 0.76 | USP2 (0.45) | FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021133038-A1 | NOVEL AMIDE DERIVATIVE USEFUL AS DIACYLGLYCEROL ACYLTRANSFERASE 2 INHIBITOR, AND USE THEREOF | 주식회사 엘지화학 | 2021-07-01 | — | — | WO | disclosed |
| CN-106255679-B | As NAThe heterocyclic compound and application thereof of V channel inhibitor | 默克专利有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-106255679-A | As Naheterocyclic compound of V channel inhibitor and application thereof | 默克专利有限公司 | 2016-12-21 | — | — | CN | disclosed |
| WO-2010138589-A1 | BICYCLIC PYRIMIDINE PI3K INHIBITOR COMPOUNDS SELECTIVE FOR P110 DELTA, AND METHODS OF USE | GENENTECH, INC. (US) | 2010-12-02 | — | — | WO | disclosed |