Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25269622 | 1.00 | FFAR3 (0.44) | FFAR3EPHX2CYP3A4HIF1AGRM5 | |
| SCHEMBL25268918 | 1.00 | FFAR3 (0.44) | FFAR3EPHX2CYP3A4HIF1AGRM5 | |
| SCHEMBL3801169 | 0.88 | FFAR3 (0.48) | FFAR3ALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL16797890 | 0.82 | USP2 (0.37) | EPHX2CYP3A4HIF1AGRM5KMT2A | |
| SCHEMBL15516069 | 0.81 | ALDH1A1 (0.44) | FFAR3EPHX2CYP3A4HIF1AGRM5 | |
| SCHEMBL27711332 | 0.78 | FFAR3 (0.50) | FFAR3HIF1AALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL14638312 | 0.78 | KMT2A (0.41) | KMT2AMEN1KDM4EGAAL3MBTL1 | |
| SCHEMBL20482260 | 0.78 | HPGD (0.43) | EPHX2KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6943029 | 0.78 | HPGD (0.43) | EPHX2KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2279068 | 0.78 | HPGD (0.43) | EPHX2KMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942575-A | Pyrrolopyridine as kinase inhibitor | 阵列生物制药公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-104926810-B | Pyrrolopyridine as kinase inhibitor | 阵列生物制药公司 | 2019-02-19 | — | — | CN | disclosed |
| EP-1326856-A1 | PYRIDINE DERIVATIVES WITH IKB-KINASE (IKK-BETA) INHIBITING ACTIVITY | Bayer Aktiengesellschaft (DE) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002024679-A1 | PYRIDINE DERIVATIVES WITH IKB-KINASE (IKK-β) INHIBITING ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-28 | — | — | WO | disclosed |